The Immunohistochemistry Antibody Company
|Human (tested or 100% immunogen sequence identity)|
|IRF3 antibody was raised against synthetic peptide derived from human IRF-3 around the phosphorylation site of Ser386.|
|IRF-3 (Phospho-Ser386) Antibody detects endogenous levels of IRF-3 only when phosphorylated at serine386.|
|PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol|
|Store at -20°C.|
|For research use only.|
IRF3 Antibody, Interferon regulatory factor 3 Antibody, IRF-3 AntibodyKey transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters.