Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Rat Monoclonal (IgG1,k) to Human IL7
Western blot, Immunoprecipitation, ELISA, Neutralization
Human (tested or 100% immunogen sequence identity)
Western blot (1 - 5 µg/ml)
Specificity and Use
IL7 antibody was raised against e. coli-expressed recombinant human IL-7.
Recognizes human Interleukin-7 (IL-7). Neutralizes human IL-7 bioactivity.
Suitable for use in ELISA, Western Blot, Immunoprecipitation and Neutralization. Western Blot: 1-5 ug/ml allows detection of 100 ng/ml recombinant IL-7 under reducing conditions. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
PBS. No preservative added.
Short term: +4°C; Long term: Add glycerol (40-50%) -20°C.
IL7 is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes.