LSBio The Immunohistochemistry Antibody Company
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA Kits
  • All Kits
  • Sandwich ELISA Kits
  • Competitive EIA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Direct ELISA Kits
  • Functional ELISA Kits
  • Phospho-Specific ELISA Kits
  • Custom ELISA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
  • Other
  • Blocking Peptides
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question?
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Publications
  • Secure Logins
  • Login to Our Secure FTP Site
  • Login to Our IHC Database
Contact Us

2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products. - To submit a new order. - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues. - To request technical information requests about an LSBio product or its application. - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Quick Order ▾
View Cart

Anti-IL1R1 Antibody (Extracellular Domain, clone 40101) IHC-plus™ LS-B2859

Note: This antibody replaces LS-C83460


Wt. Vol. Conc. Price
50 µg - 0.77 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular IL1R1 Antibodies

Anti-IL1R1 Antibody (Extracellular Domain, clone 40101) IHC-plus™ LS-B2859
Mouse Monoclonal [clone 40101] (IgG2b) to Human IL1R1
IHC - Paraffin, ELISA, Radioimmunoassay
Immunohistochemistry Image
Anti-IL1R1 Antibody (Extracellular Domain, APC) LS-C184799
Goat Polyclonal (IgG) to Human IL1R1
Flow Cytometry
APC Conjugated
Anti-IL1R1 Antibody (aa474-503) IHC-plus™ LS-B9079
Rabbit Polyclonal to Human IL1R1
IHC - Paraffin, Western blot
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 40101] (IgG2b) to Human IL1R1
IHC - Paraffin, ELISA, Radioimmunoassay


Human IL1R1
Human (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [40101]
Protein G purified


  • IHC - Paraffin (10 µg/ml)
  • Radioimmunoassay

  • Western blot

Specificity and Use

IL1R1 antibody was raised against the extracellular domain of the type I human IL-1 receptor.
Extracellular Domain
These antibodies react with cell surface and soluble human IL-1 receptor; Specific epitopes are unknown, but they do partially inhibit (30-50%) binding of one another to IL-1 receptor. They do not block binding of IL-1 to receptor, and they do not cross-react with receptors for human IL-2 or IL-4.
Immunohistochemistry: LS-B2859 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2859 was determined to be 10 ug/ml. ELISA: Can be used as capture reagents or second antibody at a concentration of 5 ug/ml. RIA: Concentrations of 20-30 ng/ml of these antibodies will bind radiolabeled IL-1 receptor in a radioimmunoassay format. Immunocytochemistry: IL-1 receptor can be detected on cultured cells using antibody concentrations of 10-100 ug/ml.


PBS, pH 7.4. Sourced in Ascites.
Long term: -70°C; Short term: -20°C; Avoid freeze-thaw cycles.
For research use only.

About IL1R1

P14778 NM_000877 NP_000868.1

IL1R1 Antibody, Antigen CD121a Antibody, D2S1473 Antibody, IL-1R-1 Antibody, IL-1R-alpha Antibody, IL-1RT-1 Antibody, IL-1RT1 Antibody, IL1R Antibody, IL1RA Antibody, IL1RT1 Antibody, Interleukin receptor 1 Antibody, Interleukin-1 receptor alpha Antibody, Interleukin-1 receptor type 1 Antibody, CD121A Antibody, CD121a antigen Antibody, Interleukin 1 receptor, type I Antibody, Interleukin-1 receptor type I Antibody, Interleukin-1 type i receptor Antibody, p80 Antibody

Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits.


Anti-IL1R1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2859 concentration 10 ug/ml.

Requested From: United States
Date Requested: 10/26/2016

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn
Copyright © 2016 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number