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Anti-HTR7 / 5HT7 Receptor Antibody (aa8-23) LS-C39057

Ordering

Wt. Vol. Conc. Price
- 100 µl - $620
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular HTR7 / 5HT7 Receptor Antibodies

Anti-HTR7 / 5HT7 Receptor Antibody (N-Terminus) IHC-plus™ LS-A6673
Rabbit Polyclonal to Human HTR7 / 5HT7 Receptor
Human, Monkey, Dog
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-HTR7 / 5HT7 Receptor Antibody (C-Terminus) IHC-plus™ LS-A7991
Rabbit Polyclonal to Human HTR7 / 5HT7 Receptor
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig
IHC - Paraffin, ELISA
Unconjugated
Immunohistochemistry Image
Anti-HTR7 / 5HT7 Receptor Antibody (aa8-23) LS-C39057
Rabbit Polyclonal (IgG) to Rat HTR7 / 5HT7 Receptor
Rat, Mouse
IHC, Immunofluorescence, Western blot
Unconjugated

100% Guaranteed 100% Guaranteed Publications Publications (1)
Rabbit Polyclonal (IgG) to Rat HTR7 / 5HT7 Receptor
Rat, Mouse
IHC, Immunofluorescence, Western blot
Unconjugated

Details

Rat HTR7 / 5HT7 Receptor
Rabbit
Rat, Mouse (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC (1:100 - 1:300)
  • Immunofluorescence
  • Western blot (1:100 - 1:250)

Specificity and Use

HTR7 / 5HT7 Receptor antibody was raised against synthetic peptide sequence corresponding to aa8 - 23 of the rat 5-HT7 receptor.
aa8-23
Recognizes Serotonin Receptor 7. Species cross-reactivity: Mouse and rat.
Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 1:100-1:250. Immunohistochemistry: 1:100-1:300 in PBS - Bn/Av-HRP Technique. Control Tissue: The antiserum demonstrates positive labeling of rat cortex and. hippocampus. Perfusion Fixation: Fixative-4% paraformaldehyde in 0.1 M Phosphate buffer, pH 7.4; 500 mL over approximately 20 minutes. Post Fixation: 4% paraformaldehyde in 0.1 M Phosphate buffer, pH 7.4; 500 mL over approximately 20 minutes. Post Fixation-1.5 hour at 4? C. in 4% paraformaldehyde in 0.1 M phosphate buffer, pH 7.4. Note: Paraformaldehyde is a necessary component in fixation of serotonin. If needed, low levels of glutaraldehyde (0.10.3%) may be used in conjunction with paraformaldehyde. Sections: 50um vibratome. Antibody dilution: 1:100-1:300 in PBS-Bn-SA/HRP Technique. Absorption control: Synthetic rat 5HT 7 receptor. Incubation on Tissue: 16-24 hours at 4?C.

Packaging

Supplied as a liquid
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

Publications (1)

1
Pharmacological stimulation of the brain serotonin receptor 7 as a novel therapeutic approach for Rett syndrome. De Filippis B, Nativio P, Fabbri A, Ricceri L, Adriani W, Lacivita E, Leopoldo M, Passarelli F, Fuso A, Laviola G. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2014 Oct;39:2506-18. [Full Text Article] [PubMed:24809912] [PMC:PMC4207333]

About HTR7 / 5HT7 Receptor

P34969 NM_019859 NP_062873.1

HTR7 Antibody, 5-HT7 Antibody, 5-HT7 receptor Antibody, 5-HT-7 Antibody, 5-hydroxytryptamine 7 receptor Antibody, 5HT7 Antibody, 5-HT-X Antibody, 5-hydroxytryptamine receptor 7 Antibody, 5HT7 Receptor Antibody, HT7 Antibody, Serotonin 5-HT7 receptor Antibody, Serotonin receptor 7 Antibody

5-HT7 Receptor (HTR7 )is a serotonin receptor with several functions, including regulation of the circadian rhythm and mediation of smooth-muscle relaxation in the vasculature and GI tract. HTR7 has been implicated in depression, autistic, and other neuropsychiatric disorders. Three protein isoforms have been documented: isoform a: 445aa; isoform b: 432aa; isoform d: 479aa.

Requested From: United States
Date Requested: 12/5/2016

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