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HTR7 / 5HT7 Receptor

5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled

5-HT7 Receptor (HTR7 )is a serotonin receptor with several functions, including regulation of the circadian rhythm and mediation of smooth-muscle relaxation in the vasculature and GI tract. HTR7 has been implicated in depression, autistic, and other neuropsychiatric disorders. Three protein isoforms have been documented: isoform a: 445aa; isoform b: 432aa; isoform d: 479aa.

Gene Name: 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
Family/Subfamily: GPCR , Serotonin
Synonyms: HTR7, 5-HT7, 5-HT7 receptor, 5-HT-7, 5-hydroxytryptamine 7 receptor, 5HT7, 5-HT-X, 5-hydroxytryptamine receptor 7, 5HT7 Receptor, HT7, Serotonin 5-HT7 receptor, Serotonin receptor 7
Target Sequences: NM_019859 NP_062873.1 P34969

Publications (4)

1
5-HT is a potent relaxant in rat superior mesenteric veins. Watts SW, Darios ES, Seitz BM, Thompson JM. Pharmacology research & perspectives. 2015 3:e00103. (IHC; Rat) [Full Text Article] [PubMed:25692021] [PMC:PMC4317234]
2
Aberrant expression of NKL homeobox genes HMX2 and HMX3 interferes with cell differentiation in acute myeloid leukemia. Stefan Nagel, Claudia Pommerenke, Corinna Meyer, Roderick A F MacLeod, Hans G Drexler. PloS one. 2020 October;15:e0240120. [Full Text Article] [PubMed:33048949] [PMC:PMC7553312] Related Antibodies: LS-C358892.
3
Expression of 5-Hydroxytryptamine Receptors in Human Urinary Bladders with Benign Prostatic Hyperplasia. Tetsuya Imamura, Osamu Ishizuka , Teruyuki Ogawa, Tomonori Minagawa, Masakuni Ishikawa, Shiro Hiragata, Hitoshi Yokoyama, Masaki Nakazawa, Yoshiki Kurizaki, Osamu Nishizawa. The Breast : official journal of the European Society of Mastology. 2015 Oct;;32:29-37. [Full Text Article] [PubMed:26391373] Related Antibodies: LS-A6673.
4
Pharmacological stimulation of the brain serotonin receptor 7 as a novel therapeutic approach for Rett syndrome. De Filippis B, Nativio P, Fabbri A, Ricceri L, Adriani W, Lacivita E, Leopoldo M, Passarelli F, Fuso A, Laviola G. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2014 Oct;39:2506-18. [Full Text Article] [PubMed:24809912] [PMC:PMC4207333] Related Antibodies: LS-C39057.
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Antibodies (37)
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HTR7 / 5HT7 Receptor (37)
Human (37)
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rabbit (35)
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Azide-free (1)
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aa47-96 (8)
aa405-433 (7)
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370-450 aa, C-terminal (1)
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aa13-28 (1)
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aa391-440 (1)
aa433-445 (1)
aa8-23 (1)
No (34)
Yes (3)
HTR7 / 5HT7 Receptor Antibody - Anti-5HT7 Receptor antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Dog, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
HTR7 / 5HT7 Receptor Antibody - Anti-5HT7 Receptor antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$440
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Fast Shipping
HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$440
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HTR7 / 5HT7 Receptor Rabbit anti-Rat Polyclonal (aa8-23) Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
100 µl/$856
HTR7 / 5HT7 Receptor Antibody - Western blot analysis of 5-HT7 expression in HEK293T (A); Raw264.7 (B); H9C2 (C) whole cell lysates.
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Dog, Rat, Human
WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
HTR7 / 5HT7 Receptor Antibody - Anti-HTR7 / 5-HT7 Receptor antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
HTR7 / 5HT7 Receptor Antibody - Anti-HT7 / 5-HT7 antibody IHC of human brain, cortex, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 19 ug/ml.
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IF, IHC, IHC-P
Unconjugated
50 µg/$440
HTR7 / 5HT7 Receptor Antibody - Anti-5HT7 Receptor antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
Fast Shipping
HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
HTR7 / 5HT7 Receptor Antibody - Western blot of 5-HT7R in human brain tissue lysate with anti-5-HT7R pcAb. A protein band of approximate molecular weight of 50 kD was detected.
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HTR7 / 5HT7 Receptor Rabbit anti-Rat Polyclonal (aa13-28) Antibody
Mouse, Dog, Rat, Human
WB
Unconjugated
0.1 mg/$386
HTR7 / 5HT7 Receptor Antibody - Anti-HTR7 / 5-HT7 Receptor antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Dog, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
HTR7 / 5HT7 Receptor Antibody - Peptide - + Immunofluorescence analysis of COS-7 cells, using HTR7 antibody.
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF
Unconjugated
100 µg/$357
HTR7 / 5HT7 Receptor Antibody - Immunohistochemistry image of paraffin-embedded human endometrial cancer at a dilution of 1:100
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (370-450 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IF
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
HTR7 / 5HT7 Receptor Antibody - Immunofluorescence analysis of COS7 cells, using HTR7 Antibody. The picture on the right is blocked with the synthesized peptide.
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (aa391-440) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
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HTR7 / 5HT7 Receptor Rabbit-New Zealand White anti-Human Polyclonal (aa150-200) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µl/$393
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (aa405-433) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (aa405-433) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (aa405-433) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (aa405-433) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (aa405-433) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (aa405-433) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
HTR7 / 5HT7 Receptor Antibody - HTR7 antibody (1 ug/ml) staining of KELLY lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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HTR7 / 5HT7 Receptor Goat anti-Human Polyclonal (aa433-445) Antibody
Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal (aa47-96) Antibody
Human
WB
Unconjugated
100 µl/$397
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HTR7 / 5HT7 Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Dog, Rat, Human
WB
Unconjugated
100 µg/$649
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).