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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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HTR4 / 5‑HT4 Receptor Antibody (Asp47) LS‑C176962
5-HT4 Receptor antibody LS-C176962 is an unconjugated rabbit polyclonal antibody to 5-HT4 Receptor (HTR4) from human, mouse and rat. Validated for IF, IHC and WB.
Catalog
Size
Price
LS-C176962-100
100 µl
Unavailable

Popular HTR4 / 5-HT4 Receptor Products

Anti-5HT4 Receptor antibody LS-A656 IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Applications: IHC, IHC - Paraffin
Anti-5HT4 Receptor antibody LS-A2685 IHC of human brain, medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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HTR4 / 5-HT34 antibody LS-C112321 Western blot of HepG2 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Immunofluorescence of MCF7 cells, using HTR4 Antibody. The picture on the right is treated with the synthesized peptide.
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Product Description

5-HT4 Receptor antibody LS-C176962 is an unconjugated rabbit polyclonal antibody to 5-HT4 Receptor (HTR4) from human, mouse and rat. Validated for IF, IHC and WB.
About HTR4 / 5-HT4 Receptor
The 5-HT4 receptor, a member of the Serotonin Receptor subfamily, has been shown to affect the sensory and motor functions of the gut. Some of the most promising emerging therapies in Irritable Bowel Syndrome revolve around targeted pharmacotherapeutic modulation of serotonin receptors (ie, 5-HT3 and 5-HT4 subtypes). At least 9 isoforms (5-HT4A-5-HT4G, and 5-HT4n) have been described, which differ in the length and composition of their intracellular C termini after a common splicing site (L358). Q13639 NM_000870 NP_000861.1

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Specifications

Target
Human HTR4 / 5-HT4 Receptor
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Immunofluorescence
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide around Asp47 of human HTR4 / 5-HT4
Epitope
Asp47
Specificity
Human HTR4 / 5-HT4
Presentation
PBS, pH 7.2, 15 mM sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

IHC of SR-4 (D47) pAb in paraffin-embedded human brain tissue.
IHC of SR-4 (D47) pAb in paraffin-embedded human brain tissue.

Western blot

Western blot of SR-4 (D47) pAb in extracts from HeLa cells.
Western blot of SR-4 (D47) pAb in extracts from HeLa cells.

Immunohistochemistry

IHC of SR-4 (D47) pAb in paraffin-embedded human brain tissue.
IHC of SR-4 (D47) pAb in paraffin-embedded human brain tissue.

Western blot

Western blot of SR-4 (D47) pAb in extracts from HeLa cells.
Western blot of SR-4 (D47) pAb in extracts from HeLa cells.

Immunohistochemistry

IHC of SR-4 (D47) pAb in paraffin-embedded human brain tissue.
IHC of SR-4 (D47) pAb in paraffin-embedded human brain tissue.

Western blot

Western blot of SR-4 (D47) pAb in extracts from HeLa cells.
Western blot of SR-4 (D47) pAb in extracts from HeLa cells.

Immunohistochemistry

IHC of SR-4 (D47) pAb in paraffin-embedded human brain tissue.
IHC of SR-4 (D47) pAb in paraffin-embedded human brain tissue.

Western blot

Western blot of SR-4 (D47) pAb in extracts from HeLa cells.
Western blot of SR-4 (D47) pAb in extracts from HeLa cells.


Requested From: 
Date Requested: 6/20/2018

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