Products
Services
Research Areas
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Reasearch Areas
Cell Cycle Pathways
Protein Family And Group
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

HTR4 / 5-HT4 Receptor

5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled

The 5-HT4 receptor, a member of the Serotonin Receptor subfamily, has been shown to affect the sensory and motor functions of the gut. Some of the most promising emerging therapies in Irritable Bowel Syndrome revolve around targeted pharmacotherapeutic modulation of serotonin receptors (ie, 5-HT3 and 5-HT4 subtypes). At least 9 isoforms (5-HT4A-5-HT4G, and 5-HT4n) have been described, which differ in the length and composition of their intracellular C termini after a common splicing site (L358). A ninth isoform (5-HT4H) results in the insertion of 14 amino acids into the second intracellular loop.

Gene Name: 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
Family/Subfamily: GPCR , Serotonin
Synonyms: HTR4, 5-HT4, 5-HT4R, 5-HT-4, 5HT4 receptor, 5-HT4 receptor, 5-hydroxytryptamine 4 receptor, 5-hydroxytryptamine receptor 4, Serotonin 5-HT-4a receptor, Serotonin receptor 4, Cardiac 5-HT4 receptor, Serotonin 4 receptor, Serotonin 5-HT-4 receptor
Target Sequences: NM_000870 NP_000861.1 Q13639

Publications (1)

1
Role of cAMP/PKA pathway and T-type calcium channels in the mechanism of action of serotonin in human adrenocortical cells. Louiset E, Duparc C, Lenglet S, Gomez-Sanchez CE, Lefebvre H. Molecular and cellular endocrinology. 2017 February;441:99-107. (Human) [Full Text Article] [PubMed:27743992] [PMC:PMC5465225] Related Antibodies: LS-A2685.

Filtered by: None
Target
HTR4 / 5-HT4 Receptor (64)
Reactivity
Human (64)
Mouse (15)
Rat (15)
Bat (14)
Bovine (19)
Chimpanzee (3)
Dog (18)
Gibbon (3)
Guinea pig (11)
Hamster (7)
Horse (21)
Monkey (25)
Pig (15)
Rabbit (18)
Application
IHC (33)
IHC-P (30)
WB (26)
ELISA (14)
ICC (5)
IF (8)
IP (1)
Peptide-ELISA (3)
Host
rabbit (63)
mouse (1)
Isotype
IgG (21)
IgG2b (1)
Clonality
monoclonal mc (1)
polyclonal pc (63)
Clone
11n173 (1)
Format
AP Conjugated (5)
APC Conjugated (5)
Azide-free (5)
Biotin Conjugated (8)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (7)
HRP Conjugated (7)
PE Conjugated (5)
Unconjugated (24)
Epitope
C-Terminus (14)
Cytoplasmic Domain (14)
aa1-30 (8)
aa144-193 (4)
110-190 aa, Internal (1)
40-120 aa, N-terminal (1)
Asn180 (1)
Asp47 (1)
N-Terminus (1)
aa131-180 (1)
aa141-190 (1)
aa21-70 (1)
Publications
No (63)
Yes (1)
Showing 1-25 of 64 results

IHC-plus™ HTR4 / 5-HT4 Receptor Antibody (Cytoplasmic Domain) LS-A2685
Publications (1)
Publications (1)
Rabbit Polyclonal to Human HTR4 / 5-HT4 Receptor
Rabbit, Dog, Bovine, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-HTR4 / 5-HT4 Receptor antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-HTR4 / 5-HT4 Receptor antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ HTR4 / 5-HT4 Receptor Antibody (Cytoplasmic Domain, Biotin) LS-A103081
Rabbit Polyclonal to Human HTR4 / 5-HT4 Receptor
Rabbit, Dog, Bovine, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
Biotin Conjugated
100µl  $650.00
Anti-HTR4 / 5-HT4 Receptor antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-HTR4 / 5-HT4 Receptor antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ HTR4 / 5-HT4 Receptor Antibody (Cytoplasmic Domain, FITC) LS-A103082
Rabbit Polyclonal to Human HTR4 / 5-HT4 Receptor
Rabbit, Dog, Bovine, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
FITC Conjugated
100µl  $650.00
Anti-HTR4 / 5-HT4 Receptor antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-HTR4 / 5-HT4 Receptor antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ HTR4 / 5-HT4 Receptor Antibody (Cytoplasmic Domain, APC) LS-A103080
Rabbit Polyclonal to Human HTR4 / 5-HT4 Receptor
Rabbit, Dog, Bovine, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-HTR4 / 5-HT4 Receptor antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-HTR4 / 5-HT4 Receptor antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ HTR4 / 5-HT4 Receptor Antibody (Cytoplasmic Domain, AP) LS-A103079
Rabbit Polyclonal to Human HTR4 / 5-HT4 Receptor
Rabbit, Dog, Bovine, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
AP Conjugated
100µl  $650.00
Anti-HTR4 / 5-HT4 Receptor antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-HTR4 / 5-HT4 Receptor antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ HTR4 / 5-HT4 Receptor Antibody (Cytoplasmic Domain, Azide-free, HRP) LS-A103083
Rabbit Polyclonal to Human HTR4 / 5-HT4 Receptor
Rabbit, Dog, Bovine, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
HRP Conjugated, Azide-free
100µl  $650.00
Anti-HTR4 / 5-HT4 Receptor antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-HTR4 / 5-HT4 Receptor antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ HTR4 / 5-HT4 Receptor Antibody (Cytoplasmic Domain, PE) LS-A103084
Rabbit Polyclonal to Human HTR4 / 5-HT4 Receptor
Rabbit, Dog, Bovine, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
PE Conjugated
100µl  $650.00
Anti-HTR4 / 5-HT4 Receptor antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-HTR4 / 5-HT4 Receptor antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ HTR4 / 5-HT4 Receptor Antibody (Cytoplasmic Domain) LS-A655
Rabbit Polyclonal to Human HTR4 / 5-HT4 Receptor
Human, Monkey
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

IHC-plus™ HTR4 / 5-HT4 Receptor Antibody (Cytoplasmic Domain, Biotin) LS-A106279
Rabbit Polyclonal to Human HTR4 / 5-HT4 Receptor
Human, Monkey
IHC, IHC-P
Biotin Conjugated
100µl  $650.00
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

IHC-plus™ HTR4 / 5-HT4 Receptor Antibody (Cytoplasmic Domain, FITC) LS-A106280
Rabbit Polyclonal to Human HTR4 / 5-HT4 Receptor
Human, Monkey
IHC, IHC-P
FITC Conjugated
100µl  $650.00
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

IHC-plus™ HTR4 / 5-HT4 Receptor Antibody (Cytoplasmic Domain, PE) LS-A106282
Rabbit Polyclonal to Human HTR4 / 5-HT4 Receptor
Human, Monkey
IHC, IHC-P
PE Conjugated
100µl  $650.00
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

IHC-plus™ HTR4 / 5-HT4 Receptor Antibody (Cytoplasmic Domain, AP) LS-A106277
Rabbit Polyclonal to Human HTR4 / 5-HT4 Receptor
Human, Monkey
IHC, IHC-P
AP Conjugated
100µl  $650.00
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

IHC-plus™ HTR4 / 5-HT4 Receptor Antibody (Cytoplasmic Domain, Azide-free, HRP) LS-A106281
Rabbit Polyclonal to Human HTR4 / 5-HT4 Receptor
Human, Monkey
IHC, IHC-P
HRP Conjugated, Azide-free
100µl  $650.00
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

IHC-plus™ HTR4 / 5-HT4 Receptor Antibody (Cytoplasmic Domain, APC) LS-A106278
Rabbit Polyclonal to Human HTR4 / 5-HT4 Receptor
Human, Monkey
IHC, IHC-P
APC Conjugated
100µl  $650.00
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

IHC-plus™ HTR4 / 5-HT4 Receptor Antibody (C-Terminus) LS-A656
Rabbit Polyclonal to Human HTR4 / 5-HT4 Receptor
Rabbit, Dog, Guinea pig, Bovine, Hamster, Horse, Bat, Human
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-5HT4 Receptor antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ HTR4 / 5-HT4 Receptor Antibody (C-Terminus) LS-A657
Rabbit Polyclonal to Human HTR4 / 5-HT4 Receptor
Pig, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-5HT4 Receptor antibody IHC of human brain, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

HTR4 / 5-HT4 Receptor Antibody (aa21-70) LS-C119371
Rabbit Polyclonal (IgG) to Human HTR4 / 5-HT4 Receptor
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunofluorescence analysis of HeLa cells, using 5-HT-4 Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from Jurkat/COLO205, using 5-HT-4 Antibody. The lane on the right is blocked with the synthesized peptide.

HTR4 / 5-HT4 Receptor Antibody (aa141-190) LS-C120546
Rabbit Polyclonal (IgG) to Human HTR4 / 5-HT4 Receptor
Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunofluorescence analysis of MCF7 cells, using HTR4 Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from NIH/3T3 cells, using HTR4 Antibody. The lane on the right is blocked with the synthesized peptide.

HTR4 / 5-HT4 Receptor Antibody (aa144-193) LS-C112321
Rabbit Polyclonal to Human HTR4 / 5-HT4 Receptor
Rabbit, Dog, Guinea pig, Bovine, Rat, Human, Monkey
WB
Unconjugated
100µl 0.5mg/ml  $365.00
HTR4 / 5-HT34 antibody Western blot of HepG2 Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

HTR4 / 5-HT4 Receptor Antibody (40-120 aa, N-terminal) LS-C386176
Rabbit Polyclonal (IgG) to Human HTR4 / 5-HT4 Receptor
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00
Western blot of SR-4 antibody

HTR4 / 5-HT4 Receptor Antibody (Asp47) LS-C176962
Rabbit Polyclonal to Human HTR4 / 5-HT4 Receptor
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
100µl  $345.00
IHC of SR-4 (D47) pAb in paraffin-embedded human brain tissue.
Western blot of SR-4 (D47) pAb in extracts from HeLa cells.

HTR4 / 5-HT4 Receptor Antibody LS-C669634
Rabbit Polyclonal (IgG) to Human HTR4 / 5-HT4 Receptor
Human
ELISA, IHC, IHC-P
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry image of paraffin-embedded human brain tissue at a dilution of 1:100
Immunohistochemistry image of paraffin-embedded human small intestine tissue at a dilution of 1:100

HTR4 / 5-HT4 Receptor Antibody (110-190 aa, Internal) LS-C386181
Rabbit Polyclonal (IgG) to Human HTR4 / 5-HT4 Receptor
Rat, Human
ELISA, IF, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00
Western blot of SR-4 antibody

HTR4 / 5-HT4 Receptor Antibody LS-C666264
Rabbit Polyclonal (IgG) to Human HTR4 / 5-HT4 Receptor
Human
ELISA, IHC, WB
Unconjugated
100µg  $355.00

HTR4 / 5-HT4 Receptor Antibody LS-C804617
Rabbit Polyclonal (IgG) to Human HTR4 / 5-HT4 Receptor
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunofluorescence Image
Western blot Image
Showing 1-25 of 64 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).