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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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HTR2B / 5‑HT2B Receptor Antibody (His55) LS‑C177075
5-HT2B Receptor antibody LS-C177075 is an unconjugated rabbit polyclonal antibody to human 5-HT2B Receptor (HTR2B). Validated for IF and WB.
Catalog
Size
Price
LS-C177075-100
100 µl
Unavailable

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Product Description

5-HT2B Receptor antibody LS-C177075 is an unconjugated rabbit polyclonal antibody to human 5-HT2B Receptor (HTR2B). Validated for IF and WB.
About HTR2B / 5-HT2B Receptor
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. P41595 NM_000867 NP_000858.3

HTR2B Antibody, 5-HT 2B receptor Antibody, 5HT2B Receptor Antibody, 5-HT(2B) Antibody, 5-HT-2B Antibody, 5-HT2b receptor Antibody, 5-HT2B Antibody, Serotonin 2b receptor Antibody, Serotonin 5-HT-2b receptor Antibody, Serotonin receptor 2B Antibody


Specifications

Target
Human HTR2B / 5-HT2B Receptor
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Immunofluorescence
  • Western blot
Immunogen
Synthetic peptide around His55 of human HTR1B / 5-HT2B
Epitope
His55
Specificity
Human HTR1B / 5-HT2B
Presentation
PBS, pH 7.2, 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of SR-2B (H55) pAb in extracts from HT-29.
Western blot of SR-2B (H55) pAb in extracts from HT-29.

Western blot

Western blot of SR-2B (H55) pAb in extracts from HT-29.
Western blot of SR-2B (H55) pAb in extracts from HT-29.

Western blot

Western blot of SR-2B (H55) pAb in extracts from HT-29.
Western blot of SR-2B (H55) pAb in extracts from HT-29.

Western blot

Western blot of SR-2B (H55) pAb in extracts from HT-29.
Western blot of SR-2B (H55) pAb in extracts from HT-29.


Requested From: 
Date Requested: 6/23/2018

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