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Anti-HSD11B1 / HSD11B Antibody (N-Terminus) LS-C24603

Ordering

Wt. Vol. Conc. Price
- 50 µl - $375
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular HSD11B1 / HSD11B Antibodies

Anti-HSD11B1 / HSD11B Antibody (aa77-92) IHC-plus™ LS-B1597
Rabbit Polyclonal (IgG) to Human HSD11B1 / HSD11B
Human, Monkey, Mouse, Rat, Hamster
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-HSD11B1 / HSD11B Antibody (aa131-145) LS-C172267
Rabbit Polyclonal to Human HSD11B1 / HSD11B
Human, Mouse, Rat
IHC - Paraffin, IHC - Frozen, ICC, Western blot
Unconjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Mouse HSD11B1 / HSD11B
Mouse, Rat, Sheep
Western blot, ELISA
Unconjugated

Details

Mouse HSD11B1 / HSD11B
Rabbit
Mouse, Rat, Sheep (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Antiserum
Unmodified

Applications

  • Western blot (1:1000 - 1:5000)
  • ELISA (1:10000 - 1:100000)

Specificity and Use

HSD11B1 / HSD11B antibody was raised against a 16aa synthetic peptide mapping near the N-terminus of mouse 11b-HSD1 (KLH coupled). Peptide sequence homology: mouse and rat: 100%; sheep: 87%; human and chicken: 81%; porcine: 75%; rabbit: 68%.
N-Terminus
Recognizes mouse 11-beta Hydroxysteroid Dehydrogenase 1 (11b-HSD1). No significant sequence homology is seen with 11b-HSD2 or other proteins.
Suitable for use in ELISA and Western Blot. Western Blot: 1:1000-1:5000 using ECL. ELISA: 1:10000-1:100000. Use 50-100 ng of control peptide.

Packaging

PBS, 0.05% sodium azide, 40% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About HSD11B1 / HSD11B

P28845 NM_005525 NP_005516.1

HSD11B1 Antibody, 11-beta-HSD1 Antibody, 11-DH Antibody, CORTRD2 Antibody, HSD11B Antibody, HSD11L Antibody, SDR26C1 Antibody, HDL Antibody, HSD11 Antibody

HSD11B1 / HSD11B is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children.

Requested From: United States
Date Requested: 12/7/2016

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