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Anti-HSD11B1 / HSD11B Antibody (aa77-92) IHC-plus™ LS-B1597

Note: This antibody replaces LS-C11690, LS-C24596, LS-B2212


Wt. Vol. Conc. Price
- 1 ea 0.6 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular HSD11B1 / HSD11B Antibodies

Anti-HSD11B1 / HSD11B Antibody (aa77-92) IHC-plus™ LS-B1597
Rabbit Polyclonal (IgG) to Human HSD11B1 / HSD11B
Human, Monkey, Mouse, Rat, Hamster
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-HSD11B1 / HSD11B Antibody (aa131-145) LS-C172267
Rabbit Polyclonal to Human HSD11B1 / HSD11B
Human, Mouse, Rat
IHC - Paraffin, IHC - Frozen, ICC, Western blot

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human HSD11B1 / HSD11B
Human, Monkey, Mouse, Rat, Hamster
IHC - Paraffin, Western blot


Human HSD11B1 / HSD11B
Human, Monkey, Mouse, Rat, Hamster (tested or 100% immunogen sequence identity)
Bovine, Dog, Guinea pig, Horse, Rabbit, Sheep (at least 90% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


  • IHC - Paraffin (5 µg/ml)
  • Western blot

Specificity and Use

HSD11B1 / HSD11B antibody was raised against human 11-HSD1 amino acids 77-92 (CLELGAASAHYIAGT). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant (100%); Sheep, Dog, Bovine, Panda, Horse, Rabbit, Guinea pig (93%); Bat, Pig (87%); Xenopus (80%).
Human 11 beta-HSD1 amino acids 77-92 (CLELGAASAHYIAGT)
Immunohistochemistry: LS-B1597 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1597 was determined to be 5 ug/ml.


TBS, pH 7.4, 5 mg/ml BSA
1 ea 500 µl sterile ddH2O
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About HSD11B1 / HSD11B

P28845 NM_005525 NP_005516.1

HSD11B1 Antibody, 11-beta-HSD1 Antibody, 11-DH Antibody, CORTRD2 Antibody, HSD11B Antibody, HSD11L Antibody, SDR26C1 Antibody, HDL Antibody, HSD11 Antibody

HSD11B1 / HSD11B is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children.


Anti-HSD11B1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1597 concentration 5 ug/ml.

Western blot

Western blot
Western blot of HSD11B1 antibody LS-B1597.

Requested From: United States
Date Requested: 10/24/2016

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