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Anti-HLA-DRB1 Antibody (aa30-58) LS-C203667

Catalog Size Price
LS-C203667-400 400 µl Unavailable

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100% Guaranteed
Rabbit Polyclonal to Human HLA-DRB1
IHC - Paraffin, Western blot, Flow Cytometry


Human HLA-DRB1
Human (tested or 100% immunogen sequence identity)
Protein A purified


  • IHC - Paraffin (1:10 - 1:50)
  • Western blot (1:1000)
  • Flow Cytometry (1:10 - 1:50)

Specificity and Use

This HLA-D_1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-58 amino acids from the N-terminal region of human HLA-D_1.


PBS, 0.09% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About HLA-DRB1

P01911 NM_002124 NP_002115.2

HLA-DRB1 Antibody, DRB1 Antibody, HLA-DR1B Antibody, HLA-DRB Antibody, Human leucocyte antigen DRB1 Antibody, MHC class II antigen DRB1*10 Antibody, MHC class II antigen Antibody, MHC class II antigen DRB1*1 Antibody, HLA-DRB2 Antibody, Lymphocyte antigen DRB1 Antibody, SS1 Antibody

Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases.


Formalin-fixed and paraffin-embedded human brain tissue reacted with HLA-DRB1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Western blot

Western blot
Western blot of HLA-DRB1 Antibody in WiDr cell line lysates (35 ug/lane). HLA-DRB1 (arrow) was detected using the purified antibody.

Western blot

Western blot
Western blot of lysates from NCI-H1299, Raji cell line (from left to right), using HLA-DRB1 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

Flow Cytometry

Flow Cytometry
Flow cytometric of widr cells using HLA-DRB1 Antibody (bottom histogram) compared to a negative control cell (top histogram)FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Requested From: 
Date Requested: 3/21/2018

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