Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 22.214.171.124] (IgG2b) to Human HLA-DR52
Human (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [126.96.36.199]
Specificity and Use
HLA-DR52 antibody was raised against hLA Class 2 Antigen DRw52.
Recognizes a polymorphic determinant on HLA-DR molecules which is associated with DR3, DR5, and DRw6 (DRw52-like). Does not react with DRw8. Recognizes part of the HLA-D molecules (29+34kD). Determinant is strongly expressed on DR3 positive cells and more weakly on DR5 and DRw6 positive cells. Species cross-reactivity: chimpanzee, Macaca apes and gorilla.
Suitable for use in Immunofluorescence: 1:10, preferably in PBS plus 1% BSA and 0.01% sodium azide.
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months.