Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
HLA-DPB1 antibody was raised against synthetic peptide located between aa98-147 of human HLA-DPB1 (P04440, NP_002112). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Rabbit (100%); Marmoset (92%).
HLA-DPB1 Antibody, Class II HLA beta chain Antibody, HLA-DP1B Antibody, MHC class II antigen DPbeta1 Antibody, MHC class II antigen DPB1 Antibody, MHC class II HLA-DRB1 Antibody, MHC HLA DPB1 Antibody, HLA-DPB Antibody, MHC class II HLA-DP-beta-1 Antibody, DPB1 Antibody, HLA DP14-beta chain Antibody, MHC class II HLA-DP-beta Antibody
HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons.