Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
HES1 Antibody, BHLHb39 Antibody, HHL Antibody, HL Antibody, Hairy and enhancer of split 1 Antibody, Hairy homolog Antibody, HRY Antibody, Hairy homolog (Drosophila) Antibody, Transcription factor HES-1 Antibody, Hairy-like protein Antibody, HES-1 Antibody
Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity).
Confocal immunofluorescence of HES1 Antibody (N-term T24) with HeLa cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue).
Western blot of anti-HES1 Antibody (N-term T24) (RB13980) in HL60 cell line lysates (35 ug/lane). HES1 (arrow) was detected using the purified antibody.
HES1 Antibody (N-term T24) flow cytometry of U251 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Requested From: United States
Date Requested: 12/10/2016