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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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HES1 / HES-1

hes family bHLH transcription factor 1

Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.

Gene Name: hes family bHLH transcription factor 1
Synonyms: HES1, BHLHb39, HHL, HL, Hairy and enhancer of split 1, Hairy homolog, HRY, Hairy homolog (Drosophila), Transcription factor HES-1, Hairy-like protein, HES-1
Target Sequences: NM_005524 NP_005515.1 Q14469

Filtered by: None
Target
HES1 / HES-1 (77)
Reactivity
Human (69)
Mouse (40)
Rat (22)
Bat (5)
Bovine (10)
Chimpanzee (3)
Gibbon (3)
Guinea pig (4)
Hamster (1)
Horse (5)
Monkey (7)
Pig (8)
Rabbit (5)
Rodent (6)
Xenopus (5)
Zebrafish (5)
Application
IHC (23)
IHC-Fr (1)
IHC-P (8)
WB (75)
Flo (5)
ELISA (17)
ICC (2)
IF (14)
IP (2)
Peptide-ELISA (3)
Host
rabbit (54)
mouse (21)
goat (1)
rat (1)
Isotype
IgG (32)
IgG1 (13)
IgG1,k (2)
IgG2a (1)
IgG2b (2)
IgG2b,k (3)
Clonality
monoclonal mc (22)
polyclonal pc (55)
Clone
4D9 (1)
7C2g2 (2)
7H11 (1)
NM1 (1)
OTI1B5 (2)
OTI1B9 (2)
OTI1F11 (2)
OTI1H8 (2)
OTI2D2 (2)
OTI2H4 (2)
OTI4H1 (1)
OTI7B9 (2)
Format
AP Conjugated (3)
APC (1)
APC Conjugated (4)
Azide-free (1)
Biotin Conjugated (6)
Carrier-free (8)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (4)
Unconjugated (46)
Epitope
C-Terminus (8)
aa21-251 (8)
aa3-32 (8)
aa22-71 (4)
N-Terminus (2)
aa1-280 (1)
aa102-137 (1)
aa142-155 (1)
aa203-236 (1)
aa205-239 (1)
aa230-280 (1)
aa24-35 (1)
aa259-293 (1)
aa3-16 (1)
aa36-143 (1)
aa9-38 (1)
Publications
No (77)
Showing 1-25 of 77 results

IHC-plus™ HES1 / HES-1 Antibody (aa24-35) LS-B2211
Rabbit Polyclonal (IgG) to Human HES1 / HES-1
Xenopus, Zebrafish, Horse, Rat, Hamster, Rabbit, Mouse, Bovine, Bat, Human, Monkey
IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
50µg 1mg/ml  $485.00
Anti-HES1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

HES1 / HES-1 Antibody (HRP) LS-C546750
Rabbit Polyclonal (IgG) to Human HES1 / HES-1
Mouse, Rodent, Human
IF, IHC, WB
HRP Conjugated
100µl  $875.00

HES1 / HES-1 Antibody (Biotin) LS-C526643
Rabbit Polyclonal (IgG) to Human HES1 / HES-1
Mouse, Rodent, Human
IF, IHC, WB
Biotin Conjugated
100µl  $875.00

HES1 / HES-1 Antibody (FITC) LS-C536635
Rabbit Polyclonal (IgG) to Human HES1 / HES-1
Mouse, Rodent, Human
IF, IHC, WB
FITC Conjugated
100µl  $875.00

HES1 / HES-1 Antibody (APC) LS-C517258
Rabbit Polyclonal (IgG) to Human HES1 / HES-1
Mouse, Rodent, Human
IF, IHC, WB
APC Conjugated
100µl  $875.00

HES1 / HES-1 Antibody (PE) LS-C654811
Rabbit Polyclonal (IgG) to Human HES1 / HES-1
Mouse, Rodent, Human
IF, IHC, WB
PE Conjugated
100µl  $875.00

IHC-plus™ HES1 / HES-1 Antibody (N-Terminus) LS-B6364
Rabbit Polyclonal (IgG) to Human HES1 / HES-1
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-HES1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
Western blot Image

HES1 / HES-1 Antibody LS-C62038
Mouse Monoclonal (IgG2b,k) to Human HES1 / HES-1
Mouse, Rat, Human
ELISA, IP, WB
Unconjugated
100µl  $305.00
Western blot Image

HES1 / HES-1 Antibody (clone OTI1B5) LS-C173601
Mouse Monoclonal [clone OTI1B5] (IgG2b) to Human HES1 / HES-1
Human
IF, IHC, IHC-P, WB
Unconjugated
100µl 0.99mg/ml  $345.00
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-HES1 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human thyroid tissue using anti-HES1 mouse monoclonal antibody.

HES1 / HES-1 Antibody (clone OTI1B5, Carrier-free) LS-C786723
Mouse Monoclonal [clone OTI1B5] (IgG2b) to Human HES1 / HES-1
Human
IF, IHC, WB
Unconjugated, Carrier-free
100µg  $395.00

HES1 / HES-1 Antibody (clone NM1) LS-C179395
Rat Monoclonal [clone NM1] (IgG2a) to Rat HES1 / HES-1
Mouse, Rat
ICC, IP, WB
Unconjugated
100µg 1mg/ml  $375.00
Immunocytochemistry Image
Western blot Image

HES1 / HES-1 Antibody (C-Terminus) LS-C134938
Rabbit Polyclonal to Rat HES1 / HES-1
Mouse, Bovine, Rat, Pig, Human
WB
Unconjugated
100µl 0.5mg/ml  $365.00
HES1 / HES-1 antibody Western Blot of Rat Kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

HES1 / HES-1 Antibody (clone OTI7B9) LS-C173600
Mouse Monoclonal [clone OTI7B9] (IgG1) to Human HES1 / HES-1
Mouse, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl 0.88mg/ml  $345.00
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-HES1 mouse monoclonal antibody.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HES1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HES1.

HES1 / HES-1 Antibody (clone OTI2D2) LS-C337570
Mouse Monoclonal [clone OTI2D2] (IgG1) to Human HES1 / HES-1
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $345.00
IHC of paraffin-embedded Human thyroid tissue using anti-HES1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
IHC of paraffin-embedded Carcinoma of Human thyroid tissue using anti-HES1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

HES1 / HES-1 Antibody (clone OTI2D2, Carrier-free) LS-C786707
Mouse Monoclonal [clone OTI2D2] (IgG1) to Human HES1 / HES-1
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100µg  $395.00

HES1 / HES-1 Antibody (aa3-32, APC) LS-C236176
Rabbit Polyclonal (IgG) to Human HES1 / HES-1
Human
ELISA, WB
APC Conjugated
200µl  $740.00

HES1 / HES-1 Antibody (aa142-155) LS-C313297
Rabbit Polyclonal to Human HES1 / HES-1
Mouse, Rat, Human
WB
Unconjugated
100µg 200µl 0.5mg/ml  $325.00
WB of HES1 / HES-1 antibody. WB: Rat Kidney Tissue Lysate.

HES1 / HES-1 Antibody (clone OTI1H8) LS-C173543
Mouse Monoclonal [clone OTI1H8] (IgG1) to Human HES1 / HES-1
Human
Flo, IF, WB
Unconjugated
100µl 1.01mg/ml  $345.00
Anti-HES1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HES1.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HES1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HES1.

HES1 / HES-1 Antibody (clone OTI1H8, Carrier-free) LS-C800031
Mouse Monoclonal [clone OTI1H8] (IgG1) to Human HES1 / HES-1
Human
Flo, IF, WB
Unconjugated, Carrier-free
100µg  $395.00

HES1 / HES-1 Antibody (aa9-38) LS-C99985
Rabbit Polyclonal to Human HES1 / HES-1
Human
Flo, IF, WB
Unconjugated
400µl  $325.00
Confocal immunofluorescence of HES1 Antibody (N-term T24) with HeLa cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue).
Western blot of anti-HES1 Antibody (N-term T24) (RB13980) in HL60 cell line lysates (35 ug/lane). HES1 (arrow) was detected using the purified antibody.

HES1 / HES-1 Antibody (aa1-280, clone OTI4H1, Carrier-free) LS-C784110
Mouse Monoclonal [clone OTI4H1] (IgG1) to Human HES1 / HES-1
Human
IF, IHC, WB
Unconjugated, Carrier-free
100µg  $395.00

HES1 / HES-1 Antibody (C-Terminus) LS-C153571
Rabbit Polyclonal to Mouse HES1 / HES-1
Mouse
ELISA, IHC, WB
Unconjugated
100µg 100µl 1mg/ml  $315.00

HES1 / HES-1 Antibody (C-Terminus, clone 7C2g2) LS-C153346
Mouse Monoclonal [clone 7C2g2] (IgG1,k) to Human HES1 / HES-1
Human
ELISA, IHC, WB
Unconjugated
100µg 100µl 1mg/ml  $305.00

HES1 / HES-1 Antibody (C-Terminus, clone 7C2g2) LS-C144560
Mouse Monoclonal [clone 7C2g2] (IgG1,k) to Human HES1 / HES-1
Human
ELISA, ICC, WB
Unconjugated
100µl  $325.00

HES1 / HES-1 Antibody LS-C806743
Rabbit Polyclonal (IgG) to Human HES1 / HES-1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Showing 1-25 of 77 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).