Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
HCN4 antibody was raised against a 15-aa peptide sequence corresponding to the cytoplasmic, C-terminus of rat HCN4 (KLH).
Recognizes rat Hyperpolarization-activated Cyclic Nucleotide-gated channel 4. Species sequence homology: (93%) rabbit and (86%) human, primate. No significant sequence homology is seen with other HCNs or any other protein.
Suitable for use in ELISA and Western Blot. Western Blot: 1:1000-1:5000. ELISA: 1:10000-1:100000 using 50-100 ng of control peptide/well.
PBS, 0.05% Sodium Azide, 40% Glycerol
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat. May contribute to the native pacemaker currents in neurons (Ih). May mediate responses to sour stimuli.