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| Catalog Number | Size | Price |
|---|---|---|
| LS-C41114-25 | 25 µg (0.5 mg/ml) | $287 |
| LS-C41114-100 | 100 µg (0.5 mg/ml) | $401 |
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Monoclonal Mouse anti‑Human H2AFX / H2AX Antibody (clone 2F3, phospho‑Ser139, IF, WB) LS‑C41114
Monoclonal Mouse anti‑Human H2AFX / H2AX Antibody (clone 2F3, phospho‑Ser139, IF, WB) LS‑C41114
Note: This antibody replaces LS-C24262
Antibody:
H2AFX / H2AX Mouse anti-Human Monoclonal (pSer139) (2F3) Antibody
Application:
ICC, IF, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
H2AFX / H2AX Mouse anti-Human Monoclonal (pSer139) (2F3) Antibody
Application:
ICC, IF, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
H2AX antibody LS-C41114 is an unconjugated mouse monoclonal antibody to human H2AX (H2AFX) (pSer139). Validated for ICC, IF and WB. Cited in 5 publications.
Target
Human H2AFX / H2AX
Synonyms
H2AFX | H2AX | Histone H2A.x | H2A.X | H2A histone family, member X | H2AX histone
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG2b
Monoclonal
Clone
2F3
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide from human H2AFX / H2AX.
Epitope
pSer139
Specificity
Modified peptide (KATQAS*QEY)
Applications
- ICC
- Immunofluorescence
- Western blot
Presentation
Phosphate-buffered solution, pH 7.2, 0.09% sodium azide.
Storage
Store at 4°C. Store undiluted.
Restrictions
For research use only. Intended for use by laboratory professionals.
About H2AFX / H2AX
LSBio Ratings
H2AFX / H2AX Antibody (phospho-Ser139, clone 2F3) for ICC, IF/Immunofluorescence, WB/Western LS-C41114 has an LSBio Rating of
Publications (4.4)
Learn more about The LSBio Ratings Algorithm
Publications (5)
Splicing regulator SC35 is essential for genomic stability and cell proliferation during mammalian organogenesis. Xiao R, Sun Y, Ding JH, Lin S, Rose DW, Rosenfeld MG, Fu XD, Li X. Molecular and cellular biology. 2007 27:5393-402.
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Rossi DJ, Bryder D, Seita J, Nussenzweig A, Hoeijmakers J, Weissman IL. Nature. 2007 447:725-9.
DNA double-strand breaks, but not crossovers, are required for the reorganization of meiotic nuclei in Tetrahymena. Mochizuki K, Novatchkova M, Loidl J. Journal of cell science. 2008 121:2148-58.
Differential roles of telomere attrition in type I and II endometrial carcinogenesis. Akbay EA, Contreras CM, Perera SA, Sullivan JP, Broaddus RR, Schorge JO, Ashfaq R, Saboorian H, Wong KK, Castrillon DH. The American journal of pathology. 2008 173:536-44.
Tetrahymena meiotic nuclear reorganization is induced by a checkpoint kinase-dependent response to DNA damage. Loidl J, Mochizuki K. Molecular biology of the cell. 2009 20:2428-37.
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Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/26/2024
Date Requested: 4/26/2024
