Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 5D6] (IgG2b) to Human GSK3B / GSK3 Beta
Rabbit Polyclonal (IgG) to Human GSK3B / GSK3 Beta
Human, Monkey, Mouse, Rat
Western blot, ELISA
Human GSK3B / GSK3 Beta
Human, Monkey, Mouse, Rat (tested or 100% immunogen sequence identity)
Protein A purified
Western blot (1:1000)
Specificity and Use
Synthetic phosphopeptide (KLH coupled) derived from the sequence of human GSK-3beta.
Detects endogenous levels of GSK-3beta only when phosphorylated at Ser9. Does not recognize the phosphorylated form of GSK-3alpha. Species cross-reactivity: human, mouse, rat, monkey. Species sequence homology: zebra fish.
Suitable for use in Western Blot and ELISA. Western Blot: 1:1000.
10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/ml BSA, 50% glycerol. No preservative added.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
GSK3B Antibody, GSK-3 beta Antibody, GSK3 beta Antibody, GSK3beta Antibody, GSK3beta isoform Antibody, TPKI Antibody, GSK 3beta Antibody, Tau protein kinase I Antibody, ZGSK-3beta Antibody
Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. Requires primed phosphorylation of the majority of its substrates.