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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GRM5 / MGLUR5 Antibody LS‑C16546
MGLUR5 antibody LS-C16546 is an unconjugated rabbit polyclonal antibody to MGLUR5 (GRM5) from mouse and rat. Validated for ICC, IF, IHC and WB.
Antibody
Catalog
Size
Price
LS-C16546-50
50 µg (0.25 mg/ml)
$740

Popular GRM5 / MGLUR5 Products

Anti-GRM5 / MGLUR5 antibody LS-A883 IHC of human colon, myenteric plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken
Applications: IHC, IHC - Paraffin
Anti-GRM5 / MGLUR5 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: Western blot, Flow Cytometry, ELISA
Anti-GRM5 / MGLUR5 antibody LS-A889 IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Monkey
Applications: IHC, IHC - Paraffin, Western blot

Product Description

MGLUR5 antibody LS-C16546 is an unconjugated rabbit polyclonal antibody to MGLUR5 (GRM5) from mouse and rat. Validated for ICC, IF, IHC and WB.

Specifications

Target
Rat GRM5 / MGLUR5
Synonyms
GRM5, GPRC1E, MGLUR5, Mglur5b, MGlu5
Host
Rabbit
Reactivity
Rat, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC (0.1 - 0.2 µg/ml)
  • ICC (0.5 µg/ml)
  • Immunofluorescence
  • Western blot (0.1 - 0.5 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
GRM5 / MGLUR5 antibody was raised against synthetic peptide corresponding to rat mGluR5 (Metabotropic Glutamate Receptor).
Specificity
Recognizes rat metabotropic glutamate receptor 5 (mGluR5). Demonstrates very little or no cross-reactivity with mGluR1a. Species cross-reactivity: rat and mouse.
Usage
Suitable for use in Western Blot, Immunohistochemistry, Immunocytochemistry and Immunofluorescence. Blocking buffer was removed. Slides were rinsed 3 times. Slides were incubated with secondary antibodies for 1 hour at RT. Slides were again rinsed 3 times and coverslipped. Staining was examined using fluorescence microscopy. Immunocytochemistry: 0.5 ug/ml. Immunofluorescence: Indirect.
Presentation
PBS, pH 7.6, 0.1% sodium azide, 40% glycerol.
Storage
Short-term: 4°C, Long-term: Add sterile 40-50% glycerol, aliquot, and store at -20°C.
Restrictions
For research use only.
About GRM5 / MGLUR5
Group I of the Metabotropic Glutamate Receptors includes GRM1 and GRM5, receptors that have been shown to activate phospholipase C. Alternative splice variants of GRM5 have been described, but their full-length nature has not been determined. Inflammation results in the activation of mGluR1 and mGluR5 in dorsal horn neurons of the spinal cord, leading to extracellular signal-regulated kinase (ERK) activation, which is required for nociceptive plasticity and enhanced pain. P41594 NM_000842 NP_000833.1


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Requested From: United States
Date Requested: 10/19/2018

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