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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GRM5 / MGLUR5

glutamate receptor, metabotropic 5

Group I of the Metabotropic Glutamate Receptors includes GRM1 and GRM5, receptors that have been shown to activate phospholipase C. Alternative splice variants of GRM5 have been described, but their full-length nature has not been determined. Inflammation results in the activation of mGluR1 and mGluR5 in dorsal horn neurons of the spinal cord, leading to extracellular signal-regulated kinase (ERK) activation, which is required for nociceptive plasticity and enhanced pain. GRM5 is involved in inflammatory mechanical hyperalgesia and potentially in schizophrenia. Summary of expresson: GRM5 has been reported to be expressed in various regions of the brain as well as in the spinal cord and dorsal root ganglia.

Gene Name: glutamate receptor, metabotropic 5
Family/Subfamily: GPCR , Metabotropic glutamate
Synonyms: GRM5, GPRC1E, MGLUR5, Mglur5b, MGlu5
Target Sequences: NM_000842 NP_000833.1 P41594

Filtered by: None
Target
GRM5 / MGLUR5 (52)
Reactivity
Human (48)
Mouse (36)
Rat (30)
Bat (14)
Bovine (14)
Chicken (8)
Dog (15)
Hamster (7)
Horse (14)
Monkey (22)
Pig (8)
Rabbit (7)
Application
IHC (32)
IHC-P (23)
WB (45)
Flo (2)
ELISA (14)
ICC (3)
IF (8)
Peptide-ELISA (2)
Host
rabbit (46)
mouse (6)
Isotype
IgG (17)
IgG1 (4)
IgG2a (1)
IgG2a,k (1)
Clonality
monoclonal mc (7)
polyclonal pc (45)
Clone
1A11D10 (1)
1B3 (1)
8H5D5 (1)
S75-3 (1)
S75-33 (1)
Format
AP Conjugated (4)
APC Conjugated (4)
Azide-free (4)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (4)
Unconjugated (28)
Epitope
C-Terminus (15)
N-Terminus (9)
aa1020-1050 (8)
40-120 aa, N-terminal (1)
Lys56 (1)
aa19-509 (1)
aa21-70 (1)
aa7-56 (1)
Publications
No (52)
Showing 1-25 of 52 results

IHC-plus™ GRM5 / MGLUR5 Antibody (C-Terminus) LS-A885
Rabbit Polyclonal to Human GRM5 / MGLUR5
Mouse, Dog, Bovine, Rat, Horse, Bat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-GRM5 / MGLUR5 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM5 / MGLUR5 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM5 / MGLUR5 Antibody (C-Terminus, Biotin) LS-A108451
Rabbit Polyclonal to Human GRM5 / MGLUR5
Mouse, Dog, Bovine, Rat, Horse, Bat, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100µl  $650.00
Anti-GRM5 / MGLUR5 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM5 / MGLUR5 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM5 / MGLUR5 Antibody (C-Terminus, FITC) LS-A108452
Rabbit Polyclonal to Human GRM5 / MGLUR5
Mouse, Dog, Bovine, Rat, Horse, Bat, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100µl  $650.00
Anti-GRM5 / MGLUR5 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM5 / MGLUR5 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM5 / MGLUR5 Antibody (C-Terminus, APC) LS-A108450
Rabbit Polyclonal to Human GRM5 / MGLUR5
Mouse, Dog, Bovine, Rat, Horse, Bat, Human, Monkey
IHC, IHC-P, WB
APC Conjugated
100µl  $650.00
Anti-GRM5 / MGLUR5 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM5 / MGLUR5 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM5 / MGLUR5 Antibody (C-Terminus, AP) LS-A108449
Rabbit Polyclonal to Human GRM5 / MGLUR5
Mouse, Dog, Bovine, Rat, Horse, Bat, Human, Monkey
IHC, IHC-P, WB
AP Conjugated
100µl  $650.00
Anti-GRM5 / MGLUR5 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM5 / MGLUR5 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM5 / MGLUR5 Antibody (C-Terminus, Azide-free, HRP) LS-A108453
Rabbit Polyclonal to Human GRM5 / MGLUR5
Mouse, Dog, Bovine, Rat, Horse, Bat, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated, Azide-free
100µl  $650.00
Anti-GRM5 / MGLUR5 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM5 / MGLUR5 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM5 / MGLUR5 Antibody (C-Terminus, PE) LS-A108454
Rabbit Polyclonal to Human GRM5 / MGLUR5
Mouse, Dog, Bovine, Rat, Horse, Bat, Human, Monkey
IHC, IHC-P, WB
PE Conjugated
100µl  $650.00
Anti-GRM5 / MGLUR5 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM5 / MGLUR5 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM5 / MGLUR5 Antibody LS-B13682
Rabbit Polyclonal (IgG)
Flo, IHC, IHC-P, WB
Unconjugated
40µg 80µl 0.5mg/ml  $425.00
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot analysis of cell lysate using 2 µg/ml Rabbit Anti-mGluR5 Polyclonal Antibody.

IHC-plus™ GRM5 / MGLUR5 Antibody (N-Terminus) LS-A883
Rabbit Polyclonal to Human GRM5 / MGLUR5
Chicken, Bovine, Rat, Hamster, Pig, Horse, Bat, Rabbit, Mouse, Dog, Human, Monkey
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-GRM5 / MGLUR5 antibody IHC of human colon, myenteric plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GRM5 / MGLUR5 Antibody (aa19-509) LS-C72508
Mouse Monoclonal (IgG1) to Human GRM5 / MGLUR5
Human
ELISA, Flo, WB
Unconjugated
100µg  $650.00

IHC-plus™ GRM5 / MGLUR5 Antibody (C-Terminus) LS-A889
Rabbit Polyclonal to Human GRM5 / MGLUR5
Human, Monkey
IHC, IHC-P, WB
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-GRM5 / MGLUR5 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM5 / MGLUR5 Antibody (C-Terminus, Biotin) LS-A108475
Rabbit Polyclonal to Human GRM5 / MGLUR5
Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100µl  $650.00
Anti-GRM5 / MGLUR5 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM5 / MGLUR5 Antibody (C-Terminus, FITC) LS-A108476
Rabbit Polyclonal to Human GRM5 / MGLUR5
Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100µl  $650.00
Anti-GRM5 / MGLUR5 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM5 / MGLUR5 Antibody (C-Terminus, PE) LS-A108478
Rabbit Polyclonal to Human GRM5 / MGLUR5
Human, Monkey
IHC, IHC-P, WB
PE Conjugated
100µl  $650.00
Anti-GRM5 / MGLUR5 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM5 / MGLUR5 Antibody (C-Terminus, Azide-free, HRP) LS-A108477
Rabbit Polyclonal to Human GRM5 / MGLUR5
Human, Monkey
IHC, IHC-P, WB
HRP Conjugated, Azide-free
100µl  $650.00
Anti-GRM5 / MGLUR5 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM5 / MGLUR5 Antibody (C-Terminus, APC) LS-A108474
Rabbit Polyclonal to Human GRM5 / MGLUR5
Human, Monkey
IHC, IHC-P, WB
APC Conjugated
100µl  $650.00
Anti-GRM5 / MGLUR5 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ GRM5 / MGLUR5 Antibody (C-Terminus, AP) LS-A108473
Rabbit Polyclonal to Human GRM5 / MGLUR5
Human, Monkey
IHC, IHC-P, WB
AP Conjugated
100µl  $650.00
Anti-GRM5 / MGLUR5 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GRM5 / MGLUR5 Antibody LS-C497585
Rabbit Monoclonal to Human GRM5 / MGLUR5
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50µl  $295.00; 100µl  $385.00; 200µl  $560.00
Immunohistochemistry of formalin-fixed paraffin-embedded (FFPE) mouse brain using GRM5 antibody at dilution of 1:100 (40x magnification).
Immunohistochemistry of paraffin-embedded rat brain using GRM5 antibodyat dilution of 1:100 (40x lens).

GRM5 / MGLUR5 Antibody (clone 1A11D10) LS-C682518
Mouse Monoclonal [clone 1A11D10] (IgG1) to Human GRM5 / MGLUR5
Human
ELISA, ICC, IHC, WB
Unconjugated
100µl  $365.00
Immunofluorescence analysis of Hela cells using GRM5 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher
Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using GRM5 mouse mAb with DAB staining.

GRM5 / MGLUR5 Antibody (N-Terminus) LS-C352288
Rabbit Polyclonal to Human GRM5 / MGLUR5
Mouse, Dog, Rat, Pig, Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $245.00
Immunohistochemical analysis of mGLUR5 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of mGLUR5 staining in EOC20 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

GRM5 / MGLUR5 Antibody (40-120 aa, N-terminal) LS-C384527
Rabbit Polyclonal (IgG) to Human GRM5 / MGLUR5
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00
Western blot of mGluR5 antibody

GRM5 / MGLUR5 Antibody LS-C16546
Rabbit Polyclonal (IgG) to Rat GRM5 / MGLUR5
Mouse, Rat
ICC, IF, IHC, WB
Unconjugated
50µg  $860.00

GRM5 / MGLUR5 Antibody (Lys56) LS-C177157
Rabbit Polyclonal to Human GRM5 / MGLUR5
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
100µl  $345.00
Western blot of mGluR5 (K56) pAb in extracts from A549 cells.

GRM5 / MGLUR5 Antibody (C-Terminus) LS-C153490
Rabbit Polyclonal to Human GRM5 / MGLUR5
Human
ELISA, IHC, WB
Unconjugated
100µg 100µl 1mg/ml  $315.00

GRM5 / MGLUR5 Antibody LS-C801356
Rabbit Polyclonal (IgG) to Human GRM5 / MGLUR5
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunofluorescence Image
Western blot Image
Showing 1-25 of 52 results

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).