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Anti-GPR39 Antibody (Extracellular Domain) IHC-plus™ LS-A139

Ordering

Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml Unavailable
Same day shipping In Stock - Same day shipping

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100% Guaranteed 100% Guaranteed In Stock In Stock Publications Publications (1)
Rabbit Polyclonal to Human GPR39
Human, Mouse, Rat, Horse, Rabbit
IHC - Paraffin
Unconjugated

Details

Human GPR39
Rabbit
Human, Mouse, Rat, Horse, Rabbit (tested or 100% immunogen sequence identity)
Monkey, Bovine, Chicken (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

IHC - Paraffin (1.25 - 2.5 µg/ml)

Specificity and Use

GPR39 antibody was raised against synthetic 16 amino acid peptide from 3rd extracellular domain of human GPR39. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Mouse, Rat, Horse, Rabbit (100%); Marmoset, Bovine, Panda, Turkey, Chicken (94%); Pig, Opossum (88%); Dog (81%).
LS-E28259 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A139. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Extracellular Domain
Human GPR39. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

Publications (1)

1
GPR39, a putative receptor of Zn2+, is region specifically localized in different lobes of the mouse prostate. Zhang Y, Zhao H, Peng H, Hu Z, Ning L, Cao Y, Tan Y, Duan E. Urology. 2011 Apr;77:1010.e1-6. [Full Text Article] [PubMed:21296392]

About GPR39

O43194 NM_001508 NP_001499.1

GPR39 Antibody, G protein-coupled receptor 39 Antibody, G-protein coupled receptor 39 Antibody

Zn2+ acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death.

Immunohistochemistry

Immunohistochemistry
Anti-GPR39 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Immunohistochemistry
Anti-GPR39 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Immunohistochemistry
Anti-GPR39 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Immunohistochemistry
Anti-GPR39 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Immunohistochemistry
Anti-GPR39 antibody LS-A139 IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Requested From: 
Date Requested: 4/26/2017

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