Zn2+ acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death.
|Gene Name:||G protein-coupled receptor 39|
|Family/Subfamily:||GPCR , Orphan-A|
|Synonyms:||GPR39, G protein-coupled receptor 39, G-protein coupled receptor 39|
|Target Sequences:||NM_001508 NP_001499.1 O43194|
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