Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Bat, Pig (tested or 100% immunogen sequence identity)
Rat, Bovine (at least 90% immunogen sequence identity)
IHC - Paraffin (1.9 µg/ml)
Specificity and Use
GPR21 antibody was raised against synthetic 14 amino acid peptide from 3rd transmembrane domain of human GPR21. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Pig, Bat (100%); Rat, Bovine (93%).
GPR21 Antibody, G protein-coupled receptor 21 Antibody
GPR21 is a member of the G-protein-coupled receptor 1 family. G-protein coupled receptors are membrane proteins which activate signaling cascades as a response to extracellular stress. The encoded protein activates a Gq signal transduction pathway which mobilizes calcium.