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Catalog Number Size Price
LS-A105-50 50 µg (0.72 mg/ml) $460 
GPR21 Antibody - Colon, Carcinoma
GPR21 Antibody - Prostate, Carcinoma
GPR21 Antibody - Ovary, carcinoma
GPR21 Antibody - Anti-GPR21 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1.4 ug/ml.
GPR21 Antibody - Anti-GPR21 antibody IHC of human pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1.4 ug/ml.
GPR21 Antibody - Colon, Carcinoma
GPR21 Antibody - Prostate, Carcinoma
GPR21 Antibody - Ovary, carcinoma
GPR21 Antibody - Anti-GPR21 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1.4 ug/ml.
GPR21 Antibody - Anti-GPR21 antibody IHC of human pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1.4 ug/ml.
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PathPlus™ Polyclonal Rabbit anti‑Human GPR21 Antibody (Cytoplasmic Domain, IHC) LS‑A105

PathPlus™ Polyclonal Rabbit anti‑Human GPR21 Antibody (Cytoplasmic Domain, IHC) LS‑A105

Antibody:
GPR21 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Pig
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$460
LS-A105-50

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
GPR21 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Pig
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
GPR21 is a member of the G-protein-coupled receptor 1 family. G-protein coupled receptors are membrane proteins which activate signaling cascades as a response to extracellular stress. The encoded protein activates a Gq signal transduction pathway which mobilizes calcium. GPR21 exerts effects on the insulin signaling pathway (for example, it attenuates signaling when overexpressed), and inhibiting GPR21 is of interest in treating diabetes. In immunohistochemistry, GPR21 has membranous positivity that is putatively most prominent in the central nervous system, although it has low to variable expression in most other tissues. It is found in the thalamus, on nonpigmented neurons in the substantia nigra, on large pyramidal neurons in the caudate, putamen and amygdala, on granule neurons in the hippocampus, in the posterior nucleus of the hypothalamus, and on populations of cells in the anterior pituitary (as well as in Herring bodies in the posterior pituitary). In peripheral tissues, it is found on hepatocytes, spermatocytic precursors, neuroendocrine cells in the small intestine, neutrophils, populations of basally-oriented cells in breast epithelium, sweat lobules in the skin, and on a few other cell types in various tissues throughout the body. References: Sci Rep. 2016; 6: 27002, PMID: 27243589
Target
Human GPR21
Synonyms
GPR21 | G protein-coupled receptor 21
Host
Rabbit
Reactivity
Human, Monkey, Pig (tested or 100% immunogen sequence identity)
Predicted
Bat, Bovine (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human GPR21. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Pig (100%); Bat, Bovine (95%); Mouse, Rat (85%).
Epitope
Cytoplasmic Domain
Specificity
Human GPR21. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC
  • IHC - Paraffin (1.4 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About GPR21
Q99679 NM_005294 NP_005285.1

Validation

GPR21 Antibody - Colon, Carcinoma
Colon, Carcinoma
Colon, Carcinoma

GPR21 Antibody - Prostate, Carcinoma
Prostate, Carcinoma
Prostate, Carcinoma

GPR21 Antibody - Ovary, carcinoma
Ovary, carcinoma
Ovary, carcinoma

GPR21 Antibody - Anti-GPR21 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1.4 ug/ml.
Anti-GPR21 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1.4 ug/ml.
Anti-GPR21 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1.4 ug/ml.

GPR21 Antibody - Anti-GPR21 antibody IHC of human pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1.4 ug/ml.
Anti-GPR21 antibody IHC of human pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1.4 ug/ml.
Anti-GPR21 antibody IHC of human pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1.4 ug/ml.

LSBio Ratings

PathPlus™ GPR21 Antibody (Cytoplasmic Domain) for IHC LS-A105 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/19/2021