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Anti-GP78 / AMFR Antibody (aa571-601) LS-C99592


Wt. Vol. Conc. Price
- 400 µl - $305
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular GP78 / AMFR Antibodies

Anti-GP78 / AMFR Antibody (N-Terminus) LS-C47058
Rabbit Polyclonal to Human GP78 / AMFR
Human, Mouse
Western blot, ELISA
Anti-GP78 / AMFR Antibody (C-Terminus) LS-C144946
Rabbit Polyclonal to Human GP78 / AMFR
Human, Mouse
IHC, Western blot
Anti-GP78 / AMFR Antibody (aa371-400) IHC-plus™ LS-B10689
Rabbit Polyclonal to Human GP78 / AMFR
IHC - Paraffin, Western blot
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human GP78 / AMFR
IHC - Paraffin, Western blot, Flow Cytometry


Human GP78 / AMFR
Human (tested or 100% immunogen sequence identity)
Ammonium sulfate precipitation


  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:1000)
  • Flow Cytometry (1:10 - 1:50)

Specificity and Use

GP78 / AMFR antibody was raised against kLH-conjugated synthetic peptide between amino acids 571-601 from human AMFR.
LS-E6909 - Lyophilized - 100 µg - $145.00


PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About GP78 / AMFR

Q9UKV5 NM_001144 NP_001135.3

AMFR Antibody, AMF receptor, isoform 1 Antibody, AMF receptor, isoform 2 Antibody, gp78 Antibody, RNF45 Antibody, RING finger protein 45 Antibody

E3 ubiquitin-protein ligase that mediates the polyubiquitination of a number of proteins such as CD3D, CYP3A4, CFTR and APOB for proteasomal degradation. Component of a VCP/p97-AMFR/gp78 complex that participates in the final step of endoplasmic reticulum-associated degradation (ERAD). The VCP/p97-AMFR/gp78 complex is involved in the sterol-accelerated ERAD degradation of HMGCR through binding to the HMGCR-INSIG complex at the ER membrane and initiating ubiquitination of HMGCR.


Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with AMFR Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.


Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

Western blot
Western blot of AMFR (arrow) using AMFR Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the AMFR gene (Lane 2) (Origene Technologies).

Flow Cytometry

Flow Cytometry
Flow cytometric of HepG2 cells using AMFR Antibody (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Requested From: United States
Date Requested: 10/28/2016

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