GP78 / AMFR

autocrine motility factor receptor, E3 ubiquitin protein ligase

E3 ubiquitin-protein ligase that mediates the polyubiquitination of a number of proteins such as CD3D, CYP3A4, CFTR and APOB for proteasomal degradation. Component of a VCP/p97-AMFR/gp78 complex that participates in the final step of endoplasmic reticulum-associated degradation (ERAD). The VCP/p97-AMFR/gp78 complex is involved in the sterol-accelerated ERAD degradation of HMGCR through binding to the HMGCR-INSIG complex at the ER membrane and initiating ubiquitination of HMGCR. The ubiquitinated HMGCR is then released from the ER by the complex into the cytosol for subsequent destruction. Also acts as a scaffold protein to assemble a complex that couples ubiquitination, retranslocation and deglycosylation. Mediates tumor invasion and metastasis as a receptor for the GPI/autocrine motility factor.

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Products

Antibodies (44)

Type

Primary (44)

Target

GP78 / AMFR (44)

Reactivity

Human (36)

Mouse (13)

Rat (5)

Bat (3)

Bovine (3)

Chicken (3)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (3)

Horse (3)

Monkey (4)

Pig (3)

Rabbit (3)

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Application

IHC (8)

IHC-P (7)

WB (40)

Flo (1)

ELISA (11)

IP (1)

Peptide-ELISA (1)

Host

rabbit (43)

mouse (1)

Product Group

IHCPlus (2)

Isotype

IgG (22)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (43)

Clone

3D9 (1)

Format

APC (2)

APC Conjugated (3)

Azide-free (1)

Biotin Conjugated (5)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (3)

Unconjugated (19)

Epitope

aa456-639 (8)

aa456-643 (8)

aa371-400 (7)

aa110-159 (4)

C-Terminus (1)

N-Terminus (1)

aa500-550 (1)

aa571-601 (1)

Publications

No (43)

Yes (1)

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GP78 / AMFR Antibody (N-Terminus) LS-C47058

(4.0) Rating

(1) Publication(s)

Antibody:

GP78 / AMFR Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 mg/$379

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IHC-plus™ GP78 / AMFR Antibody (aa371-400) LS-B10689

(4.0) Rating

Antibody:

GP78 / AMFR Rabbit anti-Human Polyclonal (aa371-400) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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GP78 / AMFR Antibody LS-C662321

Antibody:

GP78 / AMFR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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GP78 / AMFR Antibody (aa110-159) LS-C31940

Antibody:

GP78 / AMFR Rabbit anti-Human Polyclonal (aa110-159) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

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GP78 / AMFR Antibody (aa571-601) LS-C99592

Antibody:

GP78 / AMFR Rabbit anti-Human Polyclonal (aa571-601) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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GP78 / AMFR Antibody (C-Terminus) LS-C144946

Antibody:

GP78 / AMFR Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$440; 200 µl/$468

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IHC-plus™ GP78 / AMFR Antibody (aa500-550) LS-B15481

(4.0) Rating

Antibody:

GP78 / AMFR Rabbit anti-Human Polyclonal (aa500-550) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

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GP78 / AMFR Antibody LS-C669761

Antibody:

GP78 / AMFR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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GP78 / AMFR Antibody LS-C660121

Antibody:

GP78 / AMFR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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GP78 / AMFR Antibody LS-C806802

Antibody:

GP78 / AMFR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human, Monkey

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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GP78 / AMFR Antibody (clone 3D9) LS-C196653

Antibody:

GP78 / AMFR Mouse anti-Human Monoclonal (3D9) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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GP78 / AMFR Antibody LS-C660118

Antibody:

GP78 / AMFR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

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GP78 / AMFR Antibody (aa371-400) LS-C319452

Antibody:

GP78 / AMFR Rabbit anti-Human Polyclonal (aa371-400) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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GP78 / AMFR Antibody (aa371-400, Biotin) LS-C252853

Antibody:

GP78 / AMFR Rabbit anti-Human Polyclonal (aa371-400) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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GP78 / AMFR Antibody (aa371-400, FITC) LS-C252855

Antibody:

GP78 / AMFR Rabbit anti-Human Polyclonal (aa371-400) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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GP78 / AMFR Antibody (aa371-400, APC) LS-C252852

Antibody:

GP78 / AMFR Rabbit anti-Human Polyclonal (aa371-400) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

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GP78 / AMFR Antibody (aa371-400, PE) LS-C251262

Antibody:

GP78 / AMFR Rabbit anti-Human Polyclonal (aa371-400) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

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GP78 / AMFR Antibody (aa371-400, Azide-free, HRP) LS-C251261

Antibody:

GP78 / AMFR Rabbit anti-Human Polyclonal (aa371-400) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

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GP78 / AMFR Antibody LS-C781838

Antibody:

GP78 / AMFR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

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GP78 / AMFR Antibody (aa456-639) LS-C374403

Antibody:

GP78 / AMFR Rabbit anti-Mouse Polyclonal (aa456-639) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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GP78 / AMFR Antibody (aa456-639, HRP) LS-C711317

Antibody:

GP78 / AMFR Rabbit anti-Mouse Polyclonal (aa456-639) (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639

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GP78 / AMFR Antibody (aa456-639, Biotin) LS-C686957

Antibody:

GP78 / AMFR Rabbit anti-Mouse Polyclonal (aa456-639) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

• Unconjugated
• HRP
• Biotin

• Unconjugated
• HRP
• Biotin

Select

GP78 / AMFR Antibody (aa456-643) LS-C374406

Antibody:

GP78 / AMFR Rabbit anti-Human Polyclonal (aa456-643) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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GP78 / AMFR Antibody LS-C833724

Antibody:

GP78 / AMFR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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GP78 / AMFR Antibody LS-C834211

Antibody:

GP78 / AMFR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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