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Anti-GNAI1 / Gi Antibody (clone R4.5) IHC-plus™ LS-B2546

Note: This antibody replaces LS-C36537


Wt. Vol. Conc. Price
- 50 µl 0.2 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular GNAI1 / Gi Antibodies

Anti-GNAI1 / Gi Antibody (aa146-195) LS-C81891
Rabbit Polyclonal (IgG) to Human GNAI1 / Gi
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Pig, Rabbit, Zebrafish, Drosophila
Western blot
Western blot Image
Anti-GNAI1 / Gi Antibody (clone R4.5) IHC-plus™ LS-B2546
Mouse Monoclonal [clone R4.5] (IgG2b) to Rat GNAI1 / Gi
Rat, Human, Mouse, Bovine, Guinea pig
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-GNAI1 / Gi Antibody (clone 2B8-2A5) IHC-plus™ LS-B4333
Mouse Monoclonal [clone 2B8-2A5] (IgG1,k) to Human GNAI1 / Gi
IHC - Paraffin, Western blot, ELISA
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone R4.5] (IgG2b) to Rat GNAI1 / Gi
Rat, Human, Mouse, Bovine, Guinea pig
IHC - Paraffin, Western blot


Rat GNAI1 / Gi
Rat, Human, Mouse, Bovine, Guinea pig (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [R4.5]
Protein A purified


  • IHC - Paraffin (1:50)
  • Western blot

Specificity and Use

GNAI1 / Gi antibody was raised against partially purified Gai1 protein from rat brain (39-42kD). Cellular Localization: Cell membrane.
Recognizes Rat Gai1. Does not cross-react with Transducin, Gao, Gai2, Gai3, or Gas. ADP-ribosylation of ai1 proteins does not alter the reactivity. Species cross-reactivity: mouse, bovine, guinea pig and human.
Immunohistochemistry: LS-B2546 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2546 was determined to be 1:50. Positive control: IMR-5 cells; brain.


PBS, pH 7.4, 0.2% BSA, 0.1% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About GNAI1 / Gi

P63096 NM_002069 NP_002060.4

GNAI1 Antibody, Gi1 protein alpha subunit Antibody, Gi Antibody

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.


Anti-GNAI1 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2546 dilution 1:50.

Requested From: United States
Date Requested: 10/23/2016

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