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Growth Arrest Specific Gene 1 (GAS1) is a GPI-anchored plasma membrane protein. It acts as a cell cycle inhibitor by blocking the G(0) to S phase transition in both normal and transformed cells. Recent experiments have shown that Hedgehog is a ligand for GAS1 and that together they are involved in embryonic patterning.
Gene Name: | growth arrest-specific 1 |
Synonyms: | GAS1, Growth arrest-specific 1, Growth arrest-specific gene-1, GAS-1 |
Target Sequences: | NM_002048 NP_002039.2 P54826 |
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