Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton.
Immunohistochemistry with GADPH antibody at a 1:50 dilution on paraffin-embdeed mouse liver
Western blot using Glyceraldehyde-3-phosphate dehydrogenase antibody at 2.6 ug/ml. Lane 1: HepG2 whole cell lysate, Lane 2: Mouse brain lysate, Lane 3: Mouse skeletal muscle lysate
Western blot using GADPH antibody at 2 ug/ml. Lane 1, HeLa cell lysate; Lane 2, A549 cell lysate; Lane 3, HepG2 cell lysates; Lane 4, K562 cell lysate; Lane 5, Jurkat cell lysate; Lane 6, MDA-MB-231 cell lysate; Lane 7, LO2 cell lysate; Lane 8, U251 cell lysate; and Lane 9, MCF-7 cell lysate.
Western blot using GADPH antibody at 2 ug/ml. Lane 1, HeLa cell lysate; Lane 2, 293T cell lysate; Lane 3, Jurkat cell lysates; Lane 4, Mouse kidney extract; Lane 5, Rat muscle extract; Lane 6, Rat lung extract; and Lane 7, Zebrafish extract.