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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GAB2 Antibody (aa3‑30) LS‑C166308
GAB2 antibody LS-C166308 is an unconjugated rabbit polyclonal antibody to human GAB2. Validated for Flow and WB.
Catalog
Size
Price
LS-C166308-400
400 µl
Unavailable

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Product Description

GAB2 antibody LS-C166308 is an unconjugated rabbit polyclonal antibody to human GAB2. Validated for Flow and WB.
About GAB2
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis. Q9UQC2 NM_012296 NP_036428.1

GAB2 Antibody, GRB2-associated binder 2 Antibody, KIAA0571 Antibody, Pp100 Antibody


Specifications

Target
Human GAB2
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
  • Flow Cytometry (1:10 - 1:50)
Epitope
aa3-30
Specificity
This GAB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-30 amino acids from the N-terminal region of human GAB2.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of GAB2 Antibody in MCF7 cell line lysates (35 ug/lane). GAB2 (arrow) was detected using the purified antibody.
Western blot of GAB2 Antibody in MCF7 cell line lysates (35 ug/lane). GAB2 (arrow) was detected using the purified antibody.

Flow Cytometry

GAB2 Antibody flow cytometry of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
GAB2 Antibody flow cytometry of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Western blot

Western blot of GAB2 Antibody in MCF7 cell line lysates (35 ug/lane). GAB2 (arrow) was detected using the purified antibody.
Western blot of GAB2 Antibody in MCF7 cell line lysates (35 ug/lane). GAB2 (arrow) was detected using the purified antibody.

Flow Cytometry

GAB2 Antibody flow cytometry of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
GAB2 Antibody flow cytometry of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Western blot

Western blot of GAB2 Antibody in MCF7 cell line lysates (35 ug/lane). GAB2 (arrow) was detected using the purified antibody.
Western blot of GAB2 Antibody in MCF7 cell line lysates (35 ug/lane). GAB2 (arrow) was detected using the purified antibody.

Flow Cytometry

GAB2 Antibody flow cytometry of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
GAB2 Antibody flow cytometry of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Western blot

Western blot of GAB2 Antibody in MCF7 cell line lysates (35 ug/lane). GAB2 (arrow) was detected using the purified antibody.
Western blot of GAB2 Antibody in MCF7 cell line lysates (35 ug/lane). GAB2 (arrow) was detected using the purified antibody.

Flow Cytometry

GAB2 Antibody flow cytometry of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
GAB2 Antibody flow cytometry of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.


Requested From: 
Date Requested: 6/17/2018

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