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Anti-FZD4 / Frizzled 4 Antibody (Biotin) LS-C6906

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Wt. Vol. Conc. Price
50 µg 50 µl - $695
Inquire for larger quantities

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Goat Polyclonal (IgG) to Mouse FZD4 / Frizzled 4
Mouse
Western blot
Biotin Conjugated

Details

Mouse FZD4 / Frizzled 4
Goat
Mouse (tested or 100% immunogen sequence identity)
IgG Polyclonal
Biotin
Immunoaffinity purified

Applications

Western blot (0.1 - 0.2 µg/ml)

Specificity and Use

FZD4 / Frizzled 4 antibody was raised against nS0-derived rmFrizzled-4 extracellular Cysteine-Rich Domain (CRD).
Recognizes mouse Frizzled-4.
Suitable for use in Western Blot. Western Blot: Used at 0.1-0.2 ug/ml with the appropriate secondary reagents to detect mouse Frizzled-4. The detection limit for rmFrizzled-4 is ~5 ng/lane under non-reducing and reducing. conditions. In this format, this antibody shows less than 2% cross-reactivity with rmFrizzled-3, rmFrizzled-7 and rmFrizzled-8.

Packaging

Lyophilized.
50 µl deionized water
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About FZD4 / Frizzled 4

Q9ULV1 NM_012193 NP_036325.2

FZD4 Antibody, CD344 Antibody, CD344 antigen Antibody, EVR1 Antibody, Frizzled family receptor 4 Antibody, Frizzled-4 Antibody, Fz-4 Antibody, Fz4 Antibody, HFz4 Antibody, Exudative vitreoretinopathy 1 Antibody, FEVR Antibody, FZD4S Antibody, FzE4 Antibody, Frizzled 4 Antibody, Frizzled homolog 4 Antibody, WNT receptor frizzled-4 Antibody

Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin (CTNNB1) canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin (CTNNB1) and activation of Wnt target genes. Plays a critical role in retinal vascularization by acting as a receptor for Wnt proteins and norrin (NDP).

Requested From: United States
Date Requested: 9/27/2016

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