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Catalog Number Size Price
LS-A4911-50 50 µg (1 mg/ml) $460 
FZD4 / Frizzled 4 Antibody - Breast, Carcinoma
FZD4 / Frizzled 4 Antibody - Colon, Carcinoma
FZD4 / Frizzled 4 Antibody - Hodgkin's lymphoma
FZD4 / Frizzled 4 Antibody - Lung, Non Small-Cell Carcinoma
FZD4 / Frizzled 4 Antibody - Anti-FZD4 / Frizzled 4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
FZD4 / Frizzled 4 Antibody - Anti-FZD4 / Frizzled 4 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
FZD4 / Frizzled 4 Antibody - Anti-FZD4 / Frizzled 4 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
FZD4 / Frizzled 4 Antibody - Breast, Carcinoma
FZD4 / Frizzled 4 Antibody - Colon, Carcinoma
FZD4 / Frizzled 4 Antibody - Hodgkin's lymphoma
FZD4 / Frizzled 4 Antibody - Lung, Non Small-Cell Carcinoma
FZD4 / Frizzled 4 Antibody - Anti-FZD4 / Frizzled 4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
FZD4 / Frizzled 4 Antibody - Anti-FZD4 / Frizzled 4 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
FZD4 / Frizzled 4 Antibody - Anti-FZD4 / Frizzled 4 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ Polyclonal Rabbit anti‑Human FZD4 / Frizzled 4 Antibody (C‑Terminus, IHC) LS‑A4911

PathPlus™ Polyclonal Rabbit anti‑Human FZD4 / Frizzled 4 Antibody (C‑Terminus, IHC) LS‑A4911

Antibody:
FZD4 / Frizzled 4 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$460
LS-A4911-50

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
FZD4 / Frizzled 4 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
FZD4 (CD344) is a frizzled receptor that binds WNT-family proteins and plays a critical role in retinal vascularization and angiogenesis as well as maintenance of the blood brain barrier. FZD4 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and in differentiated tissues. It is also thought to function in the enteric nervous system, as it is found in neuronal and glial cells in gastrointestinal tissues in infants. In immunohistochemistry, FZD4 has cytoplasmic positivity in the brain, thyroid and adrenal glands, immune tissues, gastrointestinal tissues, the liver, the gallbladder, the pancreas, reproductive tissues, adipose tissues and skin. References: Stem Cells Int. 2016; 2016: 9076823, PMID: 26697080; Investigative Ophthalmology & Visual Science. 2011. Vol.52: 6452-6461, DOI:10.1167/iovs.10-7146;
Target
Human FZD4 / Frizzled 4
Synonyms
FZD4 | CD344 | CD344 antigen | EVR1 | Frizzled family receptor 4 | Frizzled-4 | Fz-4 | Fz4 | HFz4 | Exudative vitreoretinopathy 1 | FEVR | FZD4S | FzE4 | Frizzled 4 | Frizzled homolog 4 | WNT receptor frizzled-4
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken (tested or 100% immunogen sequence identity)
Predicted
Xenopus (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 13 amino acid peptide from C-Terminus of human FZD4 / Frizzled 4. Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Bat, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus (100%); Lizard, Xenopus (92%).
Epitope
C-Terminus
Specificity
Human FZD4 / Frizzled 4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC
  • IHC - Paraffin (25 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About FZD4 / Frizzled 4
Q9ULV1 NM_012193 NP_036325.2

Validation

FZD4 / Frizzled 4 Antibody - Breast, Carcinoma
Breast, Carcinoma
Breast, Carcinoma

FZD4 / Frizzled 4 Antibody - Colon, Carcinoma
Colon, Carcinoma
Colon, Carcinoma

FZD4 / Frizzled 4 Antibody - Hodgkin's lymphoma
Hodgkin's lymphoma
Hodgkin's lymphoma

FZD4 / Frizzled 4 Antibody - Lung, Non Small-Cell Carcinoma
Lung, Non Small-Cell Carcinoma
Lung, Non Small-Cell Carcinoma

FZD4 / Frizzled 4 Antibody - Anti-FZD4 / Frizzled 4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD4 / Frizzled 4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD4 / Frizzled 4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

FZD4 / Frizzled 4 Antibody - Anti-FZD4 / Frizzled 4 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD4 / Frizzled 4 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD4 / Frizzled 4 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

FZD4 / Frizzled 4 Antibody - Anti-FZD4 / Frizzled 4 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD4 / Frizzled 4 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD4 / Frizzled 4 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ FZD4 / Frizzled 4 Antibody (C-Terminus) for IHC LS-A4911 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/17/2021