Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Monkey, Mouse, Rat, Bovine, Horse, Pig, Rabbit
IHC - Paraffin, Western blot
Rabbit Polyclonal to Human FOXO1 / FKHR
Western blot, Immunoprecipitation
Human FOXO1 / FKHR
Human (tested or 100% immunogen sequence identity)
Specificity and Use
FOXO1 / FKHR antibody was raised against the epitope recognized maps to a region between residues 600 and the C-terminus (residue 652) of human Forkhead Box O1a using the numbering given in Swiss-Prot entry Q12778 (GeneID 2308).
Species cross-reactivity: Human. Other species have not been tested. Reactivity with mouse FOXO1a is unlikely owing to divergence of sequence between this ortholog and human FOXO1a at the site to which the epitope maps.
Suitable for use in Western Blot and Immunoprecipitation.
FOXO1 Antibody, FKHR Antibody, Forkhead in rhabdomyosarcoma Antibody, FOXO1A Antibody, FKH1 Antibody, Forkhead box protein O1 Antibody, Forkhead box protein O1A Antibody, Forkhead box O1 Antibody, Forkhead box o1a Antibody, Forkhead domain protein fkhr Antibody
Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass.