Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity).
Anti-FOXA1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6099 concentration 5 ug/ml.
Western blot of FOXA1 expression in HepG2 cell lysate.
Western blot of FOXA1 expression in transfected 293T cell line by FOXA1 monoclonal antibody.
Enzyme-Linked Immunosorbent Assay
Detection limit for recombinant GST tagged FOXA1 is approximately 0.03 ng/ml as a capture antibody.
Western blot of FOXA1 over-expressed 293 cell line, cotransfected with FOXA1 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with FOXA1 monoclonal antibody. GAPDH (36.1 kD) used as control.
Requested From: United States
Date Requested: 12/9/2016