Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone FNB11] (IgG1) to Human FN1 / Fibronectin
IHC, Western blot
Human FN1 / Fibronectin
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [FNB11]
Western blot (1:50 - 1:100)
Specificity and Use
FN1 / Fibronectin antibody was raised against recombinant fibronectin protein.
Is specific to 440 kD (non-reduced) and 220 kD (reduced) protein. Fibronectin is a dimeric glycoprotein, which is present in cells, extracellular matrix and blood. Fibronectin is involved in cells adhesion, tissue organization and wound healing.
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization.