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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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FAK / Focal Adhesion Kinase Antibody (phospho‑Tyr577) LS‑C15122
Antibody
Focal Adhesion Kinase antibody LS-C15122 is an unconjugated rabbit polyclonal antibody to Focal Adhesion Kinase (FAK) from human and mouse. Validated for ELISA and WB.
Catalog
Size
Price
LS-C15122-10
10 blot
Unavailable

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Product Description

Focal Adhesion Kinase antibody LS-C15122 is an unconjugated rabbit polyclonal antibody to Focal Adhesion Kinase (FAK) from human and mouse. Validated for ELISA and WB.
About FAK / Focal Adhesion Kinase
Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Q05397 NM_005607 NP_005598.3

PTK2 Antibody, FADK Antibody, Fadk1 Antibody, Focal adhesion kinase Antibody, FRNK Antibody, FADK 1 Antibody, Focal adhesion kinase 1 Antibody, FAK1 Antibody, p125FAK Antibody, PPP1R71 Antibody, Protein-tyrosine kinase 2 Antibody, PTK2 protein tyrosine kinase 2 Antibody, FAK Antibody, pp125 FA kinase Antibody, Pp125FAK Antibody


Specifications

Target
Human FAK / Focal Adhesion Kinase
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
  • ELISA
Immunogen
Synthetic peptide derived from a region of human FAK that contains phosphorylated Tyr577.
Epitope
pTyr577
Specificity
Recognizes human FAK. Species cross-reactivity: Mouse Species sequence homology: rat, chicken and frog.
Usage
Suitable for use in ELISA and Western Blot. Western Blot: 1:1000. Positive control: Vanadate treated chicken embryo fibroblasts expressing human FAK protein and plated on fibronectin.
Presentation
PBS (without Mg2+, Ca2+), 1 mg/ml BSA (IgG, protease free), pH 7.3, 0.1% sodium azide, 50% glycerol.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/18/2018

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