Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal to Human FAK / Focal Adhesion Kinase
IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Rabbit Polyclonal (IgG) to Human FAK / Focal Adhesion Kinase
Human, Monkey, Mouse, Rat, Dog, Horse, Rabbit, Chicken, Xenopus
ICC, Western blot
Human FAK / Focal Adhesion Kinase
Human, Monkey, Mouse, Rat, Dog, Horse, Rabbit, Chicken, Xenopus (tested or 100% immunogen sequence identity)
Western blot (1:500)
Specificity and Use
FAK / Focal Adhesion Kinase antibody was raised against synthetic peptide corresponding to amino acids 571-582 of human FAK (MEDST[pY]YKASKG-C). The immunizing sequence is identical in mouse, rat, chicken and Xenopus.
Recognizes FAK phosphorylated at Tyr576, Mr 125kD. Species cross-reactivity: Human, mouse and rat. Wide species Cross-reactivity is expected due to conservation of immunizing sequence.
Suitable for use in Western Blot, Immunocytochemistry. Western Blot: 1:500. Immunocytochemistry: 1:20.
Serum, 0.05% sodium azide, 30% glycerol.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development.