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Anti-FACT / SSRP1 Antibody (clone 10D7) LS-C41132

Ordering

Wt. Vol. Conc. Price
100 µg 200 µl 0.5 mg/ml $285
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular FACT / SSRP1 Antibodies

Anti-FACT / SSRP1 Antibody (aa490-518, AP) LS-C270430
Rabbit Polyclonal (IgG) to Human FACT / SSRP1
Human
Western blot, ELISA
AP Conjugated
Anti-FACT / SSRP1 Antibody (aa490-518, APC) LS-C270431
Rabbit Polyclonal (IgG) to Human FACT / SSRP1
Human
Western blot, ELISA
APC Conjugated
Anti-FACT / SSRP1 Antibody (aa490-518, FITC) LS-C270433
Rabbit Polyclonal (IgG) to Human FACT / SSRP1
Human
Western blot, ELISA
FITC Conjugated

100% Guaranteed 100% Guaranteed Publications Publications (2)
Mouse Monoclonal [clone 10D7] (IgG2b) to Human FACT / SSRP1
Human
Western blot
Unconjugated

Details

Human FACT / SSRP1
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [10D7]
Unconjugated
Affinity purified
Unmodified

Applications

Western blot

Specificity and Use

FACT / SSRP1 antibody was raised against recombinant human SSRP1.
Recombinant (partial)

Packaging

Phosphate-buffered solution, pH 7.2, 0.09% sodium azide at 0.5 mg/ml.
Store undiluted at 4 degrees C
For research use only.

Publications (2)

1
Histone methyltransferase SETD2 coordinates FACT recruitment with nucleosome dynamics during transcription. Carvalho S, Raposo AC, Martins FB, Grosso AR, Sridhara SC, Rino J, Carmo-Fonseca M, de Almeida SF. Nucleic acids research. 2013 41:2881-93. [PubMed:23325844] [PMC:PMC3597667]
2
Myogenin Recruits the Histone Chaperone Facilitates Chromatin Transcription (FACT) to Promote Nucleosome Disassembly at Muscle-specific Genes. Lolis AA, Londhe P, Beggs BC, Byrum SD, Tackett AJ, Davie JK. The Journal of biological chemistry. 2013 288:7676-87. [PubMed:23364797] [PMC:PMC3597808]

About FACT / SSRP1

Q08945 NM_003146 NP_003137.1

SSRP1 Antibody, Cisplatin-DNA SSRP Antibody, FACT 80 kDa subunit Antibody, FACT Antibody, High mobility group box Antibody, HSSRP1 Antibody, FACT complex subunit SSRP1 Antibody, FACT80 Antibody, FACTp80 Antibody, T160 Antibody

Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure.

Western blot

Western blot
Hela cell lysate was resolved by electrophoresis, transferred to nitrocellulose, and probed with monoclonal anti-SSRP1 antibody. Proteins were detected using a goat anti-mouse Ig secondary conjugated to HRP and a chemiluminescence detection system.
 

Requested From: United States
Date Requested: 12/8/2016

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