FACT / SSRP1

structure specific recognition protein 1

Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2 (casein kinase II). Binds specifically to double-stranded DNA and at low levels to DNA modified by the antitumor agent cisplatin. May potentiate cisplatin-induced cell death by blocking replication and repair of modified DNA. Also acts as a transcriptional coactivator for p63/TP63.

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Products

Antibodies (47)

ELISA Kits (7)

Proteins (6)

Type

Over-Expression Lysate (2)

Primary (47)

Recombinant (4)

Sandwich (7)

Target

FACT / SSRP1 (60)

Reactivity

Human (48)

Mouse (14)

Rat (10)

Bat (3)

Bovine (7)

Chicken (1)

Chimpanzee (6)

Dog (3)

Drosophila (3)

Gibbon (6)

Guinea pig (6)

Hamster (3)

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Monkey (7)

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Porcine (1)

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Application

IHC (9)

IHC-P (3)

WB (44)

ELISA (11)

ICC (1)

IF (8)

IP (6)

Peptide-ELISA (1)

Host

rabbit (43)

mouse (4)

Product Group

IHCPlus (1)

Isotype

IgG (23)

IgG1 (1)

IgG1,k (1)

IgG2b (1)

IgG2b,k (1)

Clonality

monoclonal mc (4)

polyclonal pc (43)

Clone

10D7 (1)

1D4B (2)

3E4 (1)

Format

12 x 8-Well Microstrips (2)

96-Well Strip Plate (5)

APC (1)

APC Conjugated (2)

Azide-free (1)

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Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (2)

Unconjugated (23)

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Epitope

aa6-246 (8)

aa490-518 (7)

N-Terminus (4)

aa503-552 (4)

aa611-660 (4)

aa1-50 (1)

aa150-200 (1)

aa75-338 (1)

Publications

No (59)

Yes (1)

Sample Type

Plasma (3)

Serum (3)

Tag

GST (1)

GST, N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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FACT / SSRP1 Antibody (clone 10D7) LS-C41132

(4.1) Rating

(2) Publication(s)

Antibody:

FACT / SSRP1 Mouse anti-Human Monoclonal (10D7) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

25 µg/$276; 100 µg/$352

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IHC-plus™ FACT / SSRP1 Antibody (aa150-200) LS-B13523

(4.0) Rating

Antibody:

FACT / SSRP1 Rabbit anti-Human Polyclonal (aa150-200) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µl/$485

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FACT / SSRP1 Antibody LS-C26778

Antibody:

FACT / SSRP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µg/$466

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FACT / SSRP1 Antibody LS-C482603

Antibody:

FACT / SSRP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

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FACT / SSRP1 Antibody LS-C755171

Antibody:

FACT / SSRP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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FACT / SSRP1 Antibody LS-C334698

Antibody:

FACT / SSRP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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FACT / SSRP1 Antibody LS-C748677

Antibody:

FACT / SSRP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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FACT / SSRP1 Antibody LS-C770898

Antibody:

FACT / SSRP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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FACT / SSRP1 Antibody (clone 1D4B) LS-C189755

Antibody:

FACT / SSRP1 Mouse anti-Human Monoclonal (1D4B) Antibody

Reactivity:

Human

Applications:

IF, IP, WB

Format:

Unconjugated

Price:

25 µg/$459; 100 µg/$642

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FACT / SSRP1 Antibody (clone 1D4B) LS-C189756

Antibody:

FACT / SSRP1 Mouse anti-Human Monoclonal (1D4B) Antibody

Reactivity:

Human

Applications:

IF, IP, WB

Format:

Unconjugated

Price:

100 µg/$543

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FACT / SSRP1 Antibody LS-C679643

Antibody:

FACT / SSRP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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FACT / SSRP1 Antibody (aa1-50) LS-C289768

Antibody:

FACT / SSRP1 Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

100 µl/$467

Select

FACT / SSRP1 Antibody (aa75-338) LS-C186229

Antibody:

FACT / SSRP1 Rabbit anti-Human Polyclonal (aa75-338) Antibody

Reactivity:

Mouse, Bovine, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

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FACT / SSRP1 Antibody LS-C770899

Antibody:

FACT / SSRP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

FACT / SSRP1 Antibody (aa490-518) LS-C325400

Antibody:

FACT / SSRP1 Rabbit anti-Human Polyclonal (aa490-518) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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FACT / SSRP1 Antibody (aa490-518, Biotin) LS-C270432

Antibody:

FACT / SSRP1 Rabbit anti-Human Polyclonal (aa490-518) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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FACT / SSRP1 Antibody (aa490-518, FITC) LS-C270433

Antibody:

FACT / SSRP1 Rabbit anti-Human Polyclonal (aa490-518) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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FACT / SSRP1 Antibody (aa490-518, Azide-free, HRP) LS-C270434

Antibody:

FACT / SSRP1 Rabbit anti-Human Polyclonal (aa490-518) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

FACT / SSRP1 Antibody (aa490-518, APC) LS-C270431

Antibody:

FACT / SSRP1 Rabbit anti-Human Polyclonal (aa490-518) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

FACT / SSRP1 Antibody (aa490-518, PE) LS-C270435

Antibody:

FACT / SSRP1 Rabbit anti-Human Polyclonal (aa490-518) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

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FACT / SSRP1 Antibody LS-C26777

Antibody:

FACT / SSRP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µg/$466

Select

FACT / SSRP1 Antibody LS-C803820

Antibody:

FACT / SSRP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

FACT / SSRP1 Antibody (clone 3E4) LS-C41041

Antibody:

FACT / SSRP1 Mouse anti-Human Monoclonal (3E4) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$352

Select

FACT / SSRP1 Antibody (aa503-552) LS-C109577

Antibody:

FACT / SSRP1 Rabbit anti-Human Polyclonal (aa503-552) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

FACT / SSRP1 Antibody (aa611-660) LS-C112354

Antibody:

FACT / SSRP1 Rabbit anti-Human Polyclonal (aa611-660) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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