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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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EPM2A / Laforin Antibody (aa1‑331) LS‑C123477
Antibody
Laforin antibody LS-C123477 is an unconjugated mouse monoclonal antibody to human Laforin (EPM2A). Validated for ELISA, Flow, ICC, IF, IHC, IP, RIA and WB.
Catalog
Size
Price
LS-C123477-100
100 µg
Unavailable

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Antibody
Species: Human
Applications: IHC, Western blot, ELISA

Product Description

Laforin antibody LS-C123477 is an unconjugated mouse monoclonal antibody to human Laforin (EPM2A). Validated for ELISA, Flow, ICC, IF, IHC, IP, RIA and WB.
About EPM2A / Laforin
Has both dual-specificity protein phosphatase and glucan phosphatase activities. Together with the E3 ubiquitin ligase NHLRC1/malin, appears to be involved in the clearance of toxic polyglucosan and protein aggregates via multiple pathways. Dephosphorylates phosphotyrosine, phosphoserine and phosphothreonine substrates in vitro. Has also been shown to dephosphorylate MAPT. O95278 NM_005670 NP_005661.1

EPM2A Antibody, EPM2 Antibody, LAFPTPase Antibody, LDE Antibody, Lafora PTPase Antibody, MELF Antibody, Laforin Antibody, LD Antibody


Specifications

Target
Human EPM2A / Laforin
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • ICC
  • Immunofluorescence
  • Western blot (1 µg/ml)
  • Immunoprecipitation
  • Flow Cytometry
  • ELISA
  • Radioimmunoassay
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
EPM2A / Laforin antibody was raised against purified, E. coli-derived full length recombinant human Laforin (rhLaforin; aa 1-331; Accession # O95278).
Epitope
aa1-331
Specificity
Detects endogenous human Laforin at 38kD using Western blot.
Usage
Suitable for use in RIA, Immunofluorescence, Flow Cytometry, ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry. Western Blot: 1 ug/ml.
Presentation
Supplied as lyophilized from a 0.2 um sterile-filtered solution in PBS, 5% trehalose
Reconstitution
PBS, 0.02% sodium azide.
Storage
Lyophilized powder may be stored at -20°C. Stable for 1 year at -20°C. Reconstitute by adding sterile 40-50% glycerol, aliquot and store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/18/2018

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