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Human EME1 | |
Rabbit | |
Human, Monkey, Mouse, Bat, Dog, Guinea pig, Pig, Rabbit (tested or 100% immunogen sequence identity) | |
Rat, Horse (at least 90% immunogen sequence identity) | |
Polyclonal | |
Unconjugated. Also available conjugated with Biotin, FITC, HRP. | |
Immunoaffinity purified | |
Unmodified |
EME1 antibody was raised against synthetic peptide from C-Terminus of human EME1 (Q96AY2, NP_689676). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Panda, Dog, Bat, Rabbit, Pig (100%); Rat, Elephant, Horse, Platypus (92%); Xenopus (85%). | ||
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C-Terminus | ||
Human Eme1 | ||
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody. |
Lyophilized from PBS with 2% sucrose | |
Distilled water | |
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles. | |
For research use only. |
EME1 Antibody, MMS4 Antibody, MMS4L Antibody, MMS4 homolog Antibody, SLX2A Antibody, HMMS4 Antibody
Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.
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