MUC1, CA15-3, CD227, Carcinoma-associated mucin, CD227 antigen, DF3 antigen, Episialin, Epithelial membrane antigen, H23 antigen, H23AG, Krebs von den Lungen-6, MAM6, MUC1/ZD, MUC-1/SEC, Mucin-1, Pem, KL-6, MUC-1/X, Tumor-associated mucin, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, PUM, EMA, MUC-1, Mucin 1, transmembrane
(tested or 100% immunogen sequence identity)
EMA / MUC1 antibody was raised against human milk fat globulin membrane preparation.
Reactive with 90% of breast carcinoma, most epithelial ovarian carcinoma and a high portion of the lung, urogenital and gastrointestinal carcinomas. Some reactivity is observed in the apical membrane of normal breast epithelium. Weak reactivity is also present in pancreas, kidney and lung. Reacts with a five amino acid epitope of the MUC-1 core protein which is less effective for glycosylation than most other MUC-1 epitopes. Recommended for Mamma carcinoma. Species cross-reactivity: Human.
Suitable for use in Western Blot and Immunohistochemistry (frozen tissue and paraffin sections). Immunohistochemistry: 1:10; Incubation Time 1 hr at room temperature. Antigen Localization: Cytoplasm and membrane.
PBS, pH 7.4, 0.1% Sodium Azide, 1% BSA
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.