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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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EMA / MUC1 Antibody LS‑C16631
MUC1 antibody LS-C16631 is an unconjugated mouse monoclonal antibody to human MUC1 (EMA). Validated for IHC and WB.
Antibody
Catalog
Size
Price
LS-C16631-1000
1000 µl
$650

Popular EMA / MUC1 Products

Antibody
Species: Human
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot, Flow Cytometry, ELISA
MUC1 / Episialin antibody LS-C30532 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Guinea pig, Hamster, Horse, Pig, Rabbit
Applications: IHC, IHC - Paraffin, Western blot
Anti-MUC1 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2244 dilution 1:50. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Flow Cytometry
Anti-MUC1 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4275 dilution 1:100.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin

Product Description

MUC1 antibody LS-C16631 is an unconjugated mouse monoclonal antibody to human MUC1 (EMA). Validated for IHC and WB.
About EMA / MUC1
EMA / MUC1 is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. P15941 NM_002456 NP_002447.4

MUC1 Antibody, CA15-3 Antibody, CD227 Antibody, Carcinoma-associated mucin Antibody, CD227 antigen Antibody, DF3 antigen Antibody, Episialin Antibody, Epithelial membrane antigen Antibody, H23 antigen Antibody, H23AG Antibody, Krebs von den Lungen-6 Antibody, MAM6 Antibody, MUC1/ZD Antibody, MUC-1/SEC Antibody, Mucin-1 Antibody, Pem Antibody, KL-6 Antibody, MUC-1/X Antibody, Tumor-associated mucin Antibody, Peanut-reactive urinary mucin Antibody, Polymorphic epithelial mucin Antibody, PUM Antibody, EMA Antibody, MUC-1 Antibody, Mucin 1, transmembrane Antibody


Specifications

Target
Human EMA / MUC1
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • IHC - Frozen
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
EMA / MUC1 antibody was raised against human milk fat globulin membrane preparation.
Specificity
Reactive with 90% of breast carcinoma, most epithelial ovarian carcinoma and a high portion of the lung, urogenital and gastrointestinal carcinomas. Some reactivity is observed in the apical membrane of normal breast epithelium. Weak reactivity is also present in pancreas, kidney and lung. Reacts with a five amino acid epitope of the MUC-1 core protein which is less effective for glycosylation than most other MUC-1 epitopes. Recommended for Mamma carcinoma. Species cross-reactivity: Human.
Usage
Suitable for use in Western Blot and Immunohistochemistry (frozen tissue and paraffin sections). Immunohistochemistry: 1:10; Incubation Time 1 hr at room temperature. Antigen Localization: Cytoplasm and membrane.
Presentation
PBS, pH 7.4, 0.1% Sodium Azide, 1% BSA
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/17/2018

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