Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Human EMA / MUC1
Human (tested or 100% immunogen sequence identity)
IHC - Paraffin (1:10 - 1:20)
IHC - Frozen (1:10 - 1:20)
Western blot (1:10 - 1:20)
Specificity and Use
EMA / MUC1 antibody was raised against carcinoma Associated antigen MAM6.
Recognizes Mucin 1. Reacts very strongly with most carcinomas. Occasionally shows a very weak cross-reactivity with sarcomas and leukemias. Does not react with normal intestine or colorectal adenomas, but reacts with colorectal carcinomas.
Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Immunohistochemistry (Frozen, paraffin): 1:10-1:20 diluted in PBS. Fix paraffin sections with formalin.
PBS, 0.02% sodium azide
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months
EMA / MUC1 is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas.