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Anti-EIF2AK3 / PERK Antibody (aa148-175) LS-C101136

Catalog Size Price
LS-C101136-400 400 µl Unavailable

Related Products

56 EIF2AK3 / PERK Antibodies

Most Popular EIF2AK3 / PERK Antibodies

Anti-EIF2AK3 / PERK Antibody (phospho-Thr980) LS-C38147
Rabbit Monoclonal (IgG) to Mouse EIF2AK3 / PERK
Mouse, Rat
Western blot, ELISA
Unconjugated
Anti-EIF2AK3 / PERK Antibody (aa148-175) LS-C101136
Rabbit Polyclonal to Human EIF2AK3 / PERK
Human
IHC - Paraffin, Western blot
Unconjugated
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PERK antibody (N-term Q163) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Anti-EIF2AK3 / PERK Antibody (aa947-996) LS-C118320
Rabbit Polyclonal (IgG) to Human EIF2AK3 / PERK
Human, Mouse, Rat
IHC - Paraffin, Western blot, ELISA
Unconjugated
IHC of paraffin-embedded human colon carcinoma, using PEK/PERK (Ab-981) Antibody. The picture on the right is treated with the synthesized peptide.
Anti-EIF2AK3 / PERK Antibody (clone 5G5) LS-C169265
Mouse Monoclonal [clone 5G5] (IgG1) to Human EIF2AK3 / PERK
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Western blot using EIF2AK3 monoclonal antibody against HEK293 (1) and EIF2AK3(AA: 929-1116)-hIgGFc transfected HEK293 (2) cell lysate.
Anti-EIF2AK3 / PERK Antibody (N-Terminus) LS-C353177
Rabbit Polyclonal to Human EIF2AK3 / PERK
Human
IHC - Paraffin, ICC, Immunofluorescence, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemical analysis of PERK staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.

100% Guaranteed
Rabbit Polyclonal to Human EIF2AK3 / PERK
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human EIF2AK3 / PERK
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Ammonium sulfate precipitation
Unmodified

Applications

  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:1000)

Specificity and Use

LS-E9458 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C101136. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa148-175
This PERK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-175 amino acids from the N-terminal region of human PERK.

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About EIF2AK3 / PERK

Q9NZJ5 NM_004836 NP_004827.4

EIF2AK3 Antibody, HRI Antibody, HsPEK Antibody, Pancreatic eIF2-alpha kinase Antibody, PEK Antibody, PERK Antibody, PKR-like ER kinase Antibody, WRS Antibody

Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1). Involved in control of mitochondrial morphology and function.

Immunohistochemistry

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PERK antibody (N-term Q163) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PERK antibody (N-term Q163) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Western blot

Western blot of PERK Antibody (N-term Q163) in 293 cell line lysates (35 ug/lane). PERK (arrow) was detected using the purified antibody.
Western blot of PERK Antibody (N-term Q163) in 293 cell line lysates (35 ug/lane). PERK (arrow) was detected using the purified antibody.

Requested From: 
Date Requested: 4/19/2018

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