Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
EDNRA Antibody, Endothelin receptor subtype A Antibody, Et-a-r Antibody, ETRA Antibody, Endothelin A receptor Antibody, Endothelin eta receptor Antibody, Endothelin type a receptor Antibody, Endothelin-1 receptor Antibody, ETAR Antibody, Endothelin receptor type A Antibody, HET-AR Antibody, Et-a receptor Antibody, ETA Antibody, ETA-R Antibody, Endothelin receptor: subtype a Antibody, Endothelin-1-specific receptor Antibody, ET-A Antibody, ET-RA Antibody
The ETA receptor is an Endothelin Receptor that mediates the effects of endothelin-1, a mitogen with potent contractile properties. In the human fetal olfactory epithelium cell line FNC-B4, the ETA receptor increases the secretion of gonadotropin-releasing hormone. Increased ETA concentration may be correlated with smooth muscle hypertrophy observed in patients suffering from bladder-outlet obstruction.
Confocal immunofluorescence of EDNRA Antibody with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Western blot of EDNRA antibody in CEM cell line lysates (35 ug/lane). EDNRA (arrow) was detected using the purified antibody.
Flow cytometric of CEM cells using EDNRA Antibody (green histogram) compared to a negative control cell (blue histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.