Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
The ETA receptor is an Endothelin Receptor that mediates the effects of endothelin-1, a mitogen with potent contractile properties. In the human fetal olfactory epithelium cell line FNC-B4, the ETA receptor increases the secretion of gonadotropin-releasing hormone. Increased ETA concentration may be correlated with smooth muscle hypertrophy observed in patients suffering from bladder-outlet obstruction.
|Gene Name:||endothelin receptor type A|
|Family/Subfamily:||GPCR , Endothelin|
|Synonyms:||EDNRA, Endothelin receptor subtype A, Et-a-r, ETRA, Endothelin A receptor, Endothelin eta receptor, Endothelin type a receptor, Endothelin-1 receptor, ETAR, Endothelin receptor type A, HET-AR, Et-a receptor, ETA, ETA-R, Endothelin receptor: subtype a, Endothelin-1-specific receptor, ET-A, ET-RA|
|Target Sequences:||NM_001957 NP_001948.1 P25101|
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