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Anti-DUSP26 / MKP8 Antibody (Internal) IHC-plus™ LS-A6784

Catalog Size Price
LS-A6784-50 50 µg (1 mg/ml) Unavailable
Same day shipping In Stock - Same day shipping

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Anti-DUSP26 / MKP8 Antibody (Internal) IHC-plus™ LS-A6784
Rabbit Polyclonal to Human DUSP26 / MKP8
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IHC, IHC - Paraffin, ELISA
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Anti-DUSP26 antibody LS-A6784 IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-DUSP26 / MKP8 Antibody (Internal) IHC-plus™ LS-A6785
Rabbit Polyclonal to Human DUSP26 / MKP8
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Anti-MKP-8 / DUSP26 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-DUSP26 / MKP8 Antibody (C-Terminus) IHC-plus™ LS-A6788
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Anti-MKP-8 / DUSP26 antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-DUSP26 / MKP8 Antibody (Internal) IHC-plus™ LS-A6787
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Anti-DUSP26 / MKP8 Antibody (aa1-211) LS-C372028
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Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

100% Guaranteed In Stock
Rabbit Polyclonal to Human DUSP26 / MKP8
Human, Monkey, Mouse, Rat, Bovine, Hamster, Horse, Rabbit
IHC, IHC - Paraffin, ELISA
Unconjugated

Details

Human DUSP26 / MKP8
Rabbit
Human, Monkey, Mouse, Rat, Bovine, Hamster, Horse, Rabbit (tested or 100% immunogen sequence identity)
Bat, Pig (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC
  • IHC - Paraffin (10 µg/ml)
  • ELISA

Specificity and Use

DUSP26 / MKP8 antibody was raised against synthetic 18 amino acid peptide from internal region of human DUSP26. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Hamster, Elephant, Panda, Horse, Rabbit, Opossum (100%); Bat, Pig (94%); Platypus (89%).
LS-E29179 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A6784. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Internal
Human DUSP26. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DUSP27 (61%).
Immunohistochemistry: LS-A6784 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-A6784 was determined to be 10 ug/ml.

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
For research use only.

About DUSP26 / MKP8

Q9BV47 NM_024025 NP_076930.1

DUSP26 Antibody, DSP-4 Antibody, NATA1 Antibody, SKRP3 Antibody, MAP kinase phosphatase 8 Antibody, MKP-8 Antibody, DUSP24 Antibody, LDP-4 Antibody, LDP4 Antibody, MKP8 Antibody

Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).

Immunohistochemistry

Anti-DUSP26 antibody LS-A6784 IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-DUSP26 antibody LS-A6784 IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Requested From: 
Date Requested: 5/24/2018

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