Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 6D8] (IgG1) to Human DSG2 / Desmoglein 2
Immunofluorescence, Western blot, Immunoprecipitation
Human DSG2 / Desmoglein 2
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [6D8]
Specificity and Use
For immuno fluorescence and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.
DSG2 Antibody, ARVC10 Antibody, Cadherin family member 5 Antibody, CDHF5 Antibody, CMD1BB Antibody, Desmoglein-2 Antibody, Desmoglein II Antibody, HDGC Antibody, ARVD10 Antibody, Desmoglein 2 Antibody
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18.