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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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DSC3 / Desmocollin 3 Antibody (clone 4D2) LS‑C197082
Desmocollin 3 antibody LS-C197082 is an unconjugated mouse monoclonal antibody to human Desmocollin 3 (DSC3). Validated for ELISA, IF and WB.
Catalog
Size
Price
LS-C197082-100
100 µg
Unavailable

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Species: Human, Mouse
Applications: Western blot, ELISA

Product Description

Desmocollin 3 antibody LS-C197082 is an unconjugated mouse monoclonal antibody to human Desmocollin 3 (DSC3). Validated for ELISA, IF and WB.
About DSC3 / Desmocollin 3
DSC3 / Desmocollin 3 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Q14574 NM_001941 NP_001932.2

DSC3 Antibody, CDHF3 Antibody, Cadherin family member 3 Antibody, Desmocollin-3 Antibody, Desmocollin 3 Antibody, DSC4 Antibody, HT-CP Antibody, Desmocollin-4 Antibody, DSC Antibody


Specifications

Target
Human DSC3 / Desmocollin 3
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2b,k Monoclonal [4D2]
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Applications
  • Immunofluorescence (10 µg/ml)
  • Western blot
  • ELISA
Immunogen
DSC3 (NP_001932, aa585-684 partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human DSC3 / Desmocollin 3
Usage
Sandwich ELISA: Recombinant protein. Western Blot: Recombinant protein.
Presentation
PBS, pH 7.4
Storage
Store at -20°C or lower. Aliquot to avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Immunofluorescence

Immunofluorescence of monoclonal antibody to DSC3 on A-431 cell. [antibody concentration 10 ug/ml]
Immunofluorescence of monoclonal antibody to DSC3 on A-431 cell. [antibody concentration 10 ug/ml]

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged DSC3 is approximately 1 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged DSC3 is approximately 1 ng/ml as a capture antibody.

Immunofluorescence

Immunofluorescence of monoclonal antibody to DSC3 on A-431 cell. [antibody concentration 10 ug/ml]
Immunofluorescence of monoclonal antibody to DSC3 on A-431 cell. [antibody concentration 10 ug/ml]

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged DSC3 is approximately 1 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged DSC3 is approximately 1 ng/ml as a capture antibody.

Immunofluorescence

Immunofluorescence of monoclonal antibody to DSC3 on A-431 cell. [antibody concentration 10 ug/ml]
Immunofluorescence of monoclonal antibody to DSC3 on A-431 cell. [antibody concentration 10 ug/ml]

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged DSC3 is approximately 1 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged DSC3 is approximately 1 ng/ml as a capture antibody.

Immunofluorescence

Immunofluorescence of monoclonal antibody to DSC3 on A-431 cell. [antibody concentration 10 ug/ml]
Immunofluorescence of monoclonal antibody to DSC3 on A-431 cell. [antibody concentration 10 ug/ml]

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged DSC3 is approximately 1 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged DSC3 is approximately 1 ng/ml as a capture antibody.


Requested From: 
Date Requested: 6/25/2018

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