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Anti-DNM1L / DRP1 Antibody (aa500-600) IHC-plus™ LS-B7263

Note: This antibody replaces LS-C49149

Ordering

Wt. Vol. Conc. Price
- 100 µl 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular DNM1L / DRP1 Antibodies

Anti-DNM1L / DRP1 Antibody (clone 2E7) LS-C174692
Mouse Monoclonal [clone 2E7] (IgG2b) to Human DNM1L / DRP1
Human, Monkey, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-DNM1L / DRP1 Antibody (clone 4F6) LS-C174711
Mouse Monoclonal [clone 4F6] (IgG2b) to Human DNM1L / DRP1
Human, Monkey, Mouse, Rat, Dog
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human DNM1L / DRP1
Human, Bovine
IHC - Paraffin, Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human DNM1L / DRP1
Rabbit
Human, Bovine (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated. Also available conjugated with Biotin, DY650, DY488, DY550.
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Western blot
  • (applications tested for the base form of this product only)

Specificity and Use

DNM1L / DRP1 antibody was raised against a synthetic peptide made to an internal region within residues 500-600 of the human DRP1 protein. [Swiss-Prot# O00429]. Percent identity by BLAST analysis: Bovine (100%).
aa500-600
DRP1.

Packaging

Tris-glycine buffer, 150 mM sodium chloride, 0.05% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About DNM1L / DRP1

O00429 NM_012062 NP_036192.2

DNM1L Antibody, DYMPLE Antibody, Dynamin 1-like Antibody, Dynamin-like protein Antibody, Dynamin-like protein 4 Antibody, Dynamin-like protein IV Antibody, DLP1 Antibody, Dnm1p/Vps1p-like protein Antibody, DVLP Antibody, Dynamin-related protein 1 Antibody, DYNIV-11 Antibody, DRP1 Antibody, Dynamin-1-like protein Antibody, VPS1 Antibody, EMPF Antibody, HDYNIV Antibody

Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage.

Immunohistochemistry

Immunohistochemistry
Anti-DNM1L antibody IHC of human brain, cerebellum, Purkinje. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7263 concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
Lane 1: DRP1 knockout Lane 2: DRP1 wild type MEFs Stained at 1:500x dilution. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 12/9/2016

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